Evidence map›Paper›PMID 22576563›Full record

ArticleObesity surgery2012

Evaluation of gastric fundus invagination for weight loss in a porcine model.

Elias Darido, D Wayne Overby, Kim A Brownley, Timothy M Farrell

Abstract read
PubMed Publisher
In one paragraph

Article in Obesity surgery, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.6field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Elias DaridoDepartment of Surgery CB 7081, UNC Department of Surgery, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599-7081, USA. elias721@hotmail.com
D Wayne Overby
Kim A Brownley
Timothy M Farrell
University of North Carolina at Chapel Hill · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gastric fundus compliance allows stomach volume increase in response to food intake. Absence of this postprandial relaxation alters hormonal signals and induces early satiety and weight loss. This study demonstrates the effect of gastric fundus invagination on the growth rate of juvenile pigs. After institutional animal care and use committee approval, 15 juvenile pigs were divided into two groups. In the first group, six pigs were anesthetized, weighed, and submitted to laparotomy, stomach manipulation, and short gastric vessel ligation. This is the control group and is referred to as "Sham". In the second group, gastric fundus invagination was added by using a circular stapler. This is the procedure group and is designated as "GFI". Postoperatively, body weight and food intake were measured for 5 weeks. Pigs were euthanized and the stomachs examined. Growth patterns were compared. Three animals were excluded from the analysis. At the end of the 5-week study period, six GFI pigs had intact anastomosis with an invaginated fundus. The mean percent growth rate for the GFI group (54.2 ± 2.8 %) was significantly less than the Sham group (77.7 ± 4.9 %). Gastric fundus invagination significantly decreases the growth rate in juvenile pigs.

Indexed as

Weight LossAnimalsBody WeightDisease Models, AnimalEatingFemaleFundoplicationGastric FundusObesityRandom AllocationSwine

Identifiers

PMID22576563
OpenAlexW1967218755

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.