Evidence map›Paper›PMID 22576228›Full record

ReviewMolecules (Basel, Switzerland)2012

Fluorescent nanoprobes dedicated to in vivo imaging: from preclinical validations to clinical translation.

Juliette Mérian, Julien Gravier, Fabrice Navarro, Isabelle Texier

Abstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

44 citing papers in PubMed.

  1. Article
  2. Article
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  7. Article
  8. CD38-specific nanobodies allowFrontiers in immunology · 2022
    Article
  9. Review
  10. Ovarian Accumulation of Nanoemulsions: Impact of Mice Age and Particle Size.International journal of molecular sciences · 2021
    Article
  11. Review
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Fluorescence Imaging Using Indocyanine Green Dye in the Pediatric Population.The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG · 2020
    Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Juliette MérianDépartement MicroTechnologies Pour la Biologie et la Santé CEA-LETI, Minatec, 17 Rue des Martyrs, 38045 Grenoble Cedex, France.
Julien Gravier
Fabrice Navarro
Isabelle Texier

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

With the fast development, in the last ten years, of a large choice of set-ups dedicated to routine in vivo measurements in rodents, fluorescence imaging techniques are becoming essential tools in preclinical studies. Human clinical uses for diagnostic and image-guided surgery are also emerging. In comparison to low-molecular weight organic dyes, the use of fluorescent nanoprobes can improve both the signal sensitivity (better in vivo optical properties) and the fluorescence biodistribution (passive "nano" uptake in tumours for instance). A wide range of fluorescent nanoprobes have been designed and tested in preclinical studies for the last few years. They will be reviewed and discussed considering the obstacles that need to be overcome for their potential everyday use in clinics. The conjugation of fluorescence imaging with the benefits of nanotechnology should open the way to new medical applications in the near future.

Indexed as

Fluorescent DyesMolecular ProbesNanoparticlesDiagnostic ImagingFluorescenceHumansNeoplasmsQuantum DotsSpectroscopy, Near-InfraredSurgery, Computer-AssistedTissue DistributionTranslational Research, BiomedicalFluorescent DyesMolecular Probes

Identifiers

PMID22576228
PMCPMC6268987

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.