Evidence map›Paper›PMID 22576175›Full record

ArticleBioinformatics (Oxford, England)2012

CalMaTe: a method and software to improve allele-specific copy number of SNP arrays for downstream segmentation.

Maria Ortiz-Estevez, Ander Aramburu, Henrik Bengtsson, Pierre Neuvial, Angel Rubio

Abstract read
In one paragraph

Article in Bioinformatics (Oxford, England), 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. 'Multi-omic' data analysis using O-miner.Briefings in bioinformatics · 2019
    Article
  3. Article
  4. Article
  5. Article
  6. Observational
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Getting DNA copy numbers without control samples.Algorithms for molecular biology : AMB · 2012
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Maria Ortiz-EstevezCEIT and TECNUN, University of Navarra, 20018 San Sebastian, Spain.
Ander Aramburu
Henrik Bengtsson
Pierre Neuvial
Angel Rubio

Funding

The Berkeley Cancer Genome CenterU24CA126551 · NCI · UNIVERSITY OF CALIF-LAWRENC BERKELEY LAB · PI GRAY, JOE W. · 2006 to 2009
$5.4M
NCI NIH HHS U24 CA126551
6 · The paper itself

Abstract

summaryCalMaTe calibrates preprocessed allele-specific copy number estimates (ASCNs) from DNA microarrays by controlling for single-nucleotide polymorphism-specific allelic crosstalk. The resulting ASCNs are on average more accurate, which increases the power of segmentation methods for detecting changes between copy number states in tumor studies including copy neutral loss of heterozygosity. CalMaTe applies to any ASCNs regardless of preprocessing method and microarray technology, e.g. Affymetrix and Illumina. AVAILABILITY: The method is available on CRAN (http://cran.r-project.org/) in the open-source R package calmate, which also includes an add-on to the Aroma Project framework (http://www.aroma-project.org/).

Indexed as

AllelesPolymorphism, Single NucleotideSoftwareHumansNeoplasmsOligonucleotide Array Sequence Analysis

Identifiers

PMID22576175
PMCPMC3381965

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.