ArticlePlant foods for human nutrition (Dordrecht, Netherlands)2012
In vitro utilization of gold and green kiwifruit oligosaccharides by human gut microbial populations.
Article in Plant foods for human nutrition (Dordrecht, Netherlands), 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.
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Who cites it
15 citing papers in PubMed, 2 syntheses or guidelines pooled it, 41 citations in OpenAlex.
- Effect of fruit intake on functional constipation: A systematic review and meta-analysis of randomized and crossover studies.Frontiers in nutrition · 2022Pooled it
- Kiwifruit and Kiwifruit Extracts for Treatment of Constipation: A Systematic Review and Meta-Analysis.Canadian journal of gastroenterology & hepatology · 2022Pooled it
- The Effect of Apple and Pear Cultivars on In Vitro Fermentation with Human Faecal Microbiota.Microorganisms · 2025Article
- Randomized, Placebo-Controlled, Double-Blind 8-Week Trial on the Efficacy of A Proprietary Kiwifruit Extract on Constipation-Predominant Irritable Bowel Syndrome.JGH open : an open access journal of gastroenterology and hepatology · 2025Article
- Shotgun Metagenomic Sequencing Revealed the Prebiotic Potential of a Fruit Juice Drink with Fermentable Fibres in Healthy Humans.Foods (Basel, Switzerland) · 2023Article
- Constipation-Predominant Irritable Bowel Syndrome (IBS-C): Effects of Different Nutritional Patterns on Intestinal Dysbiosis and Symptoms.Nutrients · 2023Review
- Biocatalytical Acyl-Modification of Puerarin: Shape Gut Microbiota Profile and Improve Short Chain Fatty Acids Production in Rats.Plant foods for human nutrition (Dordrecht, Netherlands) · 2022Article
- Dietary Proteins Alter Fermentation Characteristics of Human Gut Microbiota In Vitro.Plant foods for human nutrition (Dordrecht, Netherlands) · 2021Article
- Bioaminergic Responses in an In Vitro System Studying Human Gut Microbiota-Kiwifruit Interactions.Microorganisms · 2020Article
- Does an Apple a Day Also Keep the Microbes Away? The Interplay Between Diet, Microbiota, and Host Defense Peptides at the Intestinal Mucosal Barrier.Frontiers in immunology · 2020Review
- A Pilot Study of the Effect of Green Kiwifruit on Human Intestinal Fermentation Measured by Hydrogen and Methane Breath Testing.Journal of medicinal food · 2018Article
- Consumption of kiwifruit capsules increasesJournal of nutritional science · 2017Article
- The Use of Green Leaf Membranes to Promote Appetite Control, Suppress Hedonic Hunger and Loose Body Weight.Plant foods for human nutrition (Dordrecht, Netherlands) · 2015Article
- The role of the gut microbiome in the pathogenesis and treatment of obesity.Global advances in health and medicine · 2014Review
- Digested and fermented green kiwifruit increases human β-defensin 1 and 2 production in vitro.Plant foods for human nutrition (Dordrecht, Netherlands) · 2012Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We examined the effects of whole kiwifruit on gut microbiota using an in vitro batch model of gastric-ileal digestion and colonic fermentation. Faecal fermentations of gold and green kiwifruit, inulin and water (control) digests were performed for up to 48 h. As compared to the control, gold and green kiwifruit increased Bifidobacterium spp. by 0.9 and 0.8 log(10) cfu/ml, respectively (P < 0.001), and the Bacteroides-Prevotella-Porphyromonas group by 0.4 and 0.5 log(10) cfu/ml, respectively. Inulin only had a bifidogenic effect (+0.4 log(10) cfu/ml). This was accompanied with increases in microbial glycosidases, especially those with substrate specificities relating to the breakdown of kiwifruit oligosaccharides, and with increased generation of short chain fatty acids. The microbial metabolic activity was sustained for up to 48 h, which we attribute to the complexity of the carbohydrate substrate provided by whole kiwifruit. Kiwifruit fermenta supernatant was also separately shown to affect the in vitro proliferation of Bifidobacterium longum, and its adhesion to Caco-2 intestinal epithelial cells. Collectively, these data suggest that whole kiwifruit may modulate human gut microbial composition and metabolism to produce metabolites conducive to increased bifidobacteria-host association.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.