Evidence map›Paper›PMID 22575477›Full record

ArticleCurrent biology : CB2012

Cell size control in yeast.

Jonathan J Turner, Jennifer C Ewald, Jan M Skotheim

Open access · bronzeAbstract read
In one paragraph

Article in Current biology : CB, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 187 papers.

0numbers the graph read from it
0cells of the map it votes in
187citing papers in PubMed
11.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

187 citing papers in PubMed, 354 citations in OpenAlex.

  1. Article
  2. A phase oscillator model of cell cycles reveals nuclear density control in a branched fungal network.Proceedings of the National Academy of Sciences of the United States of America · 2026
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  15. TheCells · 2025
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  18. Expression of 1,3-β-glucan synthase subunits inAntimicrobial agents and chemotherapy · 2025
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  20. Article

127 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Jonathan J TurnerDepartment of Biology, Stanford University, Stanford, CA 94305, USA.
Jennifer C Ewald
Jan M Skotheim
Stanford University · US

Funding

Supplement to Enhance Wellness and Resiliency in the Graduate EnvironmentT32GM007276 · NIGMS · STANFORD UNIVERSITY · PI MORRISON, ASHBY J. · 1985 to 2023
$32.9M
Mechanisms of restriction point response to dynamic growth factor signalsR01GM092925 · NIGMS · STANFORD UNIVERSITY · PI SKOTHEIM, JAN M · 2010 to 2018
$2.8M
NIGMS NIH HHS GM007276NIGMS NIH HHS GM092925NIGMS NIH HHS R01 GM092925NIGMS NIH HHS T32 GM007276Wellcome Trust
6 · The paper itself

Abstract

Cell size is an important adaptive trait that influences nearly all aspects of cellular physiology. Despite extensive characterization of the cell-cycle regulatory network, the molecular mechanisms coupling cell growth to division, and thereby controlling cell size, have remained elusive. Recent work in yeast has reinvigorated the size control field and suggested provocative mechanisms for the distinct functions of setting and sensing cell size. Further examination of size-sensing models based on spatial gradients and molecular titration, coupled with elucidation of the pathways responsible for nutrient-modulated target size, may reveal the fundamental principles of eukaryotic cell size control.

Indexed as

Cell SizeSalmonella typhimurium

Identifiers

PMID22575477
PMCPMC3350643
OpenAlexW2172213445

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.