ReviewEndocrinology and metabolism clinics of North America2012
Closed-loop insulin delivery in type 1 diabetes.
Review in Endocrinology and metabolism clinics of North America, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Continuous subcutaneous insulin infusion versus multiple daily injections of insulin for pregnant women with diabetes.The Cochrane database of systematic reviews · 2016Pooled it
- Hydrogel-based approaches to target hypersensitivity mechanisms underlying autoimmune disease.Advanced drug delivery reviews · 2024Review
- A Glucose-Responsive Cannula for Automated and Electronics-Free Insulin Delivery.Advanced materials (Deerfield Beach, Fla.) · 2024Article
- Review
- Intelligent automated drug administration and therapy: future of healthcare.Drug delivery and translational research · 2021Review
- A New Optimized Percutaneous Access System for CIPII.Journal of diabetes science and technology · 2017Article
- Continuous subcutaneous insulin infusion in diabetes: patient populations, safety, efficacy, and pharmacoeconomics.Diabetes/metabolism research and reviews · 2016Review
- Clinical results of an automated artificial pancreas using technosphere inhaled insulin to mimic first-phase insulin secretion.Journal of diabetes science and technology · 2015Article
- Automated control of an adaptive bihormonal, dual-sensor artificial pancreas and evaluation during inpatient studies.IEEE transactions on bio-medical engineering · 2014Article
- Can glucose be monitored accurately at the site of subcutaneous insulin delivery?Journal of diabetes science and technology · 2014Review
- Insulin therapy in children and adolescents with type 1 diabetes.Paediatric drugs · 2014Review
- Dexcom G4AP: an advanced continuous glucose monitor for the artificial pancreas.Journal of diabetes science and technology · 2013Article
- Multivariable adaptive closed-loop control of an artificial pancreas without meal and activity announcement.Diabetes technology & therapeutics · 2013Article
- Neurodegeneration in the pathogenesis of diabetic retinopathy: molecular mechanisms and therapeutic implications.Current medicinal chemistry · 2013Review
- Italian contributions to the development of continuous glucose monitoring sensors for diabetes management.Sensors (Basel, Switzerland) · 2012Review
- Outpatient Management of Pediatric Type 1 Diabetes.The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAGReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
Advances in diabetes technology have led to significant improvements in the quality of life and care received by individuals with diabetes. Despite this, achieving tight glycemic control through intensive insulin therapy and modern insulin regimens is challenging because of the barrier of hypoglycemia, the most feared complication of insulin therapy as reported by patients, caregivers, and physicians. This article outlines the individual components of the closed-loop system together with the existing clinical evidence. The artificial pancreas prototypes currently used in clinical studies are reviewed as well as obstacles and limitations facing the technology.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.