ArticlePsychoneuroendocrinology2012
Neuroendocrine predictors of emotional and behavioral adjustment in boys: longitudinal follow-up of a community sample.
Article in Psychoneuroendocrinology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 21 citations in OpenAlex.
- Saliva Collection Methods Among Children and Adolescents: A Scoping Review.Molecular diagnosis & therapy · 2024Article
- Gender Differences in Cortisol and Cortisol Receptors in Depression: A Narrative Review.International journal of molecular sciences · 2023Review
- Impact of the Social and Natural Environment on Preschool-Age Children Weight.International journal of environmental research and public health · 2018Article
- Impact of Psychosocial Environment on Young Children's Emotional and Behavioral Difficulties.International journal of environmental research and public health · 2017Article
- Adolescent Physiological and Behavioral Patterns of Emotion Dysregulation Predict Multisystemic Therapy Response.Journal of emotional and behavioral disorders · 2017Article
- Child cortisol moderates the association between family routines and emotion regulation in low-income children.Developmental psychobiology · 2017Article
- Childhood adversity and epigenetic regulation of glucocorticoid signaling genes: Associations in children and adults.Development and psychopathology · 2016Review
- Differential relations between youth internalizing/externalizing problems and cortisol responses to performance vs. interpersonal stress.Stress (Amsterdam, Netherlands) · 2016Article
- Dispositional and Environmental Predictors of the Development of Internalizing Problems in Childhood: Testing a Multilevel Model.Journal of abnormal child psychology · 2015Article
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Authors and funding
8 authors at 5 institutions in 1 country.
Funding
Abstract
backgroundDysregulation of the hypothalamic-pituitary-adrenal (HPA) axis has been observed in adults and children with mood and anxiety disorders and is thought to be involved in the pathogenesis of these disorders. We recently studied a diverse community sample of boys and found associations of behavioral problems, including symptoms of depression and anxiety, with basal and stress-induced cortisol concentrations. Here we examine cortisol-emotional/behavioral associations at a two-year follow-up and test whether initial cortisol is predictive of worsening emotional/behavioral problems two years later.
methodSeventy-eight 10-14-year-old boys and their mothers completed a battery of psychosocial assessments, provided morning and afternoon saliva samples, and participated in a home visit involving mildly stressful tasks and saliva collection for cortisol assay during a two-year follow-up assessment.
resultsConsistent with the findings from our time 1 assessment, greater declines in cortisol across the home-visit challenge task were significantly associated with internalizing and externalizing behaviors as well as attention problems and social problems at the two-year follow-up. In addition, morning and afternoon cortisol concentrations at the initial assessment were significant positive predictors of the later development of child depressive symptoms at follow-up after controlling for initial depressive symptoms.
conclusionThese findings demonstrate that children in the community with internalizing and externalizing behavior problems have altered patterns of HPA axis stress reactivity. In addition, our prospective findings suggest that elevated cortisol concentrations may influence the later development of emotional/behavioral problems in boys.
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