Evidence map›Paper›PMID 22575214›Full record

ReviewSeminars in cancer biology2012

Epithelial to mesenchymal transition: new and old insights from the classical neural crest model.

Pablo H Strobl-Mazzulla, Marianne E Bronner

Abstract readReview
In one paragraph

Review in Seminars in cancer biology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Specifying neural crest cells: From chromatin to morphogens and factors in between.Wiley interdisciplinary reviews. Developmental biology · 2018
    Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Review
  20. DNA methyltransferase 3B regulates duration of neural crest production via repression of Sox10.Proceedings of the National Academy of Sciences of the United States of America · 2014
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Pablo H Strobl-MazzullaLaboratory of Developmental Biology, Instituto de Investigaciones Biotecnológicas-Instituto Tecnológico de Chascomús (CONICET-UNSAM), Chascomús, Argentina. strobl@intech.gov.ar
Marianne E Bronner

Funding

Transcriptional Casualty in Embryonic Morphogenesis: from the Specifications GRNP01HD037105 · NICHD · CALIFORNIA INSTITUTE OF TECHNOLOGY · PI DAVIDSON, ERIC H · 1999 to 2018
$27.1M
The role of PHD12 in epigenetic control of cranial neural crest EMTR03DE022521 · NIDCR · CALIFORNIA INSTITUTE OF TECHNOLOGY · PI BRONNER, MARIANNE, STROBL MAZZULLA, PABLO HERNAN · 2011 to 2013
$173k
NICHD NIH HHS HD037105NICHD NIH HHS P01 HD037105NIDCR NIH HHS R03 DE022521NIDCR NIH HHS R03DE022521
6 · The paper itself

Abstract

The epithelial-to-mesenchymal transition (EMT) is an important event converting compact and ordered epithelial cells into migratory mesenchymal cells. Given the molecular and cellular similarities between pathological and developmental EMTs, studying this event during neural crest development offers and excellent in vivo model for understanding the mechanisms underlying this process. Here, we review new and old insight into neural crest EMT in search of commonalities with cancer progression that might aid in the design of specific therapeutic prevention.

Indexed as

Epithelial-Mesenchymal TransitionAdherens JunctionsAnimalsCadherinsEpigenesis, GeneticExtracellular MatrixHumansNeural CrestTranscription FactorsCadherinsTranscription Factors

Identifiers

PMID22575214
PMCPMC3435443

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.