Evidence map›Paper›PMID 22574797›Full record

Trial reportBritish journal of clinical pharmacology2013

Dose-independent kinetics with low level exposure to nicotine and cotinine.

Neal L Benowitz, Delia Dempsey, Rachel F Tyndale, Gideon St Helen, Peyton Jacob

Abstract readLetterRandomized Controlled Trial
In one paragraph

Trial report in British journal of clinical pharmacology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. CYP2A6 Effects on Subjective Reactions to Initial Smoking Attempt.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2016
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Neal L Benowitz
Delia Dempsey
Rachel F Tyndale
Gideon St Helen
Peyton Jacob

Funding

University of Toronto Coordinating Genetics Core & Clinical Trial SiteU01DA020830 · NIDA · UNIVERSITY OF PENNSYLVANIA · PI CINCIRIPINI, PAUL MICHAEL · 2005 to 2014
$22.4M
Research Support CoreP30DA012393 · NIDA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI ST.HELEN, GIDEON · 1999 to 2024
$17.1M
Postdoctoral training in tobacco controlR25CA113710 · NCI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI GLANTZ, STANTON ARNOLD · 2006 to 2015
$5.4M
CIHR MOP86471CIHR TMH-109787NCI NIH HHS R25 CA113710NIDA NIH HHS DA12393NIDA NIH HHS P30 DA012393NIDA NIH HHS U01 DA 020830NIDA NIH HHS U01 DA020830
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AdultAllelesAryl Hydrocarbon HydroxylasesCotinineCross-Over StudiesCytochrome P-450 CYP2A6FemaleHumansMaleMiddle AgedNicotineAryl Hydrocarbon HydroxylasesCotinineCytochrome P-450 CYP2A6Nicotine

Identifiers

PMID22574797
PMCPMC3555070

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.