ArticleJournal of clinical microbiology2012
Enzootic enteropathogenic Escherichia coli infection in laboratory rabbits.
Article in Journal of clinical microbiology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 31 citations in OpenAlex.
- Multidrug-ResistantAntibiotics (Basel, Switzerland) · 2025Article
- Acute phase proteins as potent early biomarkers for the detection ofOpen veterinary journal · 2025Article
- Diseases of domestic rabbits by purpose; a retrospective study of 2,583 cases received at 4 diagnostic laboratories in California, USA, 2013-2022.Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc · 2024Article
- A One Health Perspective for Defining and DecipheringComparative medicine · 2021Review
- Prebiotic supplementation effect onPeerJ · 2021Article
- Intestinal colonization of genotoxic Escherichia coli strains encoding colibactin and cytotoxic necrotizing factor in small mammal pets.Veterinary microbiology · 2020Article
- Application ofAnimals : an open access journal from MDPI · 2019Article
- Article
- Biosecurity practices and causes of enteritis on Ontario meat rabbit farms.The Canadian veterinary journal = La revue veterinaire canadienne · 2017Article
- Characterization of Rabbit Nucleotide-Binding Oligomerization Domain 1 (NOD1) and the Role of NOD1 Signaling Pathway during Bacterial Infection.Frontiers in immunology · 2017Article
- Recent advances in understanding enteric pathogenic Escherichia coli.Clinical microbiology reviews · 2013Review
- Enteropathogenic Escherichia coli prevalence in laboratory rabbits.Veterinary microbiology · 2013Article
- Gastrointestinal disease in guinea pigs and rabbits.The veterinary clinics of North America. Exotic animal practice · 2013Review
- Enteric infection and subsequent septicemia due to attaching and effacing Escherichia coli in a Chinchilla.Comparative medicine · 2013Article
- Multicausal etiology of the enteric syndrome in rabbits from Mexico.Revista Argentina de microbiologiaArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 2 institutions in 2 countries.
Funding
Abstract
Enteropathogenic Escherichia coli (EPEC) is the most important cause of persistent diarrhea in children, particularly in developing countries. Animals serve as pathogenic E. coli reservoirs, and compelling evidence for cross-species EPEC transmission exists. In this report, enzootic EPEC infection associated with up to 10.5% diarrhea-associated morbidity in a large laboratory Dutch Belted rabbit colony was investigated. These rabbits were obtained from a commercial vendor and had acute diarrhea following shipment. Fecal culture of 20 rabbits yielded 48 E. coli isolates, 83% of which were eae positive. Repetitive sequence-based PCR (REP-PCR) and serologic analysis identified a single disease-associated EPEC O145:H2 strain. In sampled rabbits, EPEC-positive culture and the presence of diarrhea were significantly associated. This strain displayed a localized adherence-like HEp-2 cell adherence pattern, as seen in diarrheic human infant EPEC isolates. Treatment was instituted with the fluoroquinolone antibiotic enrofloxacin, to which all isolates were susceptible. Preshipment parenteral enrofloxacin administration reduced diarrhea-associated morbidity 22-fold and mortality 12-fold in subsequent deliveries. This report emphasizes the zoonotic potential of animal EPEC strains and the need for virulence determinant-based screening of E. coli isolates from diarrheic animals.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.