ReviewCurrent topics in behavioral neurosciences2013
Neurobiological markers of familial risk for depression.
Review in Current topics in behavioral neurosciences, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03779477 (Effect of "Coping With Stress Program" to Depression and Anxiety Symptoms and Brain Functions in Adolescent at High-Risk for Depression), which is not on this map. Cited by 13 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effect of "Coping With Stress Program" to Depression and Anxiety Symptoms and Brain Functions in Adolescent at High-Risk for Depression
Who cites it
13 citing papers in PubMed, 19 citations in OpenAlex.
- Polygenic Risks for Depression and Neural Responses to Reward and Punishment in Young Adults.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2025Article
- Multiple domains of risk factors for first onset of depression in adolescent girls.Journal of affective disorders · 2021Article
- Risk of Depression in the Offspring of Parents with Depression: The Role of Emotion Regulation, Cognitive Style, Parenting and Life Events.Child psychiatry and human development · 2020Article
- Increased ASL-CBF in the right amygdala predicts the first onset of depression in healthy young first-degree relatives of patients with major depression.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2020Article
- Orbital and Medial Prefrontal Cortex Functional Connectivity of Major Depression Vulnerability and Disease.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2018Article
- Prefrontal brain responsiveness to negative stimuli distinguishes familial risk for major depression from acute disorder.Journal of psychiatry & neuroscience : JPN · 2017Article
- Influence of Familial Risk for Depression on Cortico-Limbic Connectivity During Implicit Emotional Processing.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2017Article
- Cortisol Awakening Response and Internalizing Symptoms Across Childhood: Exploring the Role of Age and Externalizing Symptoms.International journal of behavioral development · 2016Article
- Predicting first onset of depression in young girls: Interaction of diurnal cortisol and negative life events.Journal of abnormal psychology · 2015Article
- A neural substrate for behavioral inhibition in the risk for major depressive disorder.Journal of the American Academy of Child and Adolescent Psychiatry · 2015Article
- Brain structural alterations associated with young women with subthreshold depression.Scientific reports · 2015Article
- Fetal exposure to maternal depressive symptoms is associated with cortical thickness in late childhood.Biological psychiatry · 2015Article
- Targeted Rejection Triggers Differential Pro- and Anti-Inflammatory Gene Expression in Adolescents as a Function of Social Status.Clinical psychological science : a journal of the Association for Psychological Science · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
Major depression is associated with a wide range of neurobiological disturbances, including anomalies in the structure and function of cortical and subcortical gray matter and dysregulation of the HPA axis. In this chapter, we review research demonstrating that many of these abnormalities are also present in never-depressed offspring of adults with recurrent depression and discuss how such findings might reflect dysfunctional neuroregulatory systems that precede the onset of this disorder. We also briefly discuss candidate genes and environmental factors that have been posited to be directly involved in the transmission of neural and HPA-axis abnormalities from depressed parents to their offspring, and we review how, by obtaining a better understanding of the neurobiological markers of depression risk, we can facilitate the development of targeted strategies for the prevention and treatment of major depression.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.