ReviewAmerican journal of Alzheimer's disease and other dementias2012
A clinical approach to early-onset inheritable dementia.
Review in American journal of Alzheimer's disease and other dementias, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Updated meta-analysis of the role of APOE ε2/ε3/ε4 alleles in frontotemporal lobar degeneration.Oncotarget · 2017Pooled it
- An Integrative Literature Review on the Nomenclature and Definition of Dementia at a Young Age.Journal of Alzheimer's disease : JAD · 2021Review
- Differentiated clinical presentation of early and late-onset Alzheimer's disease: is 65 years of age providing a reliable threshold?Journal of neurology · 2015Article
- NRG3 gene is associated with the risk and age at onset of Alzheimer disease.Journal of neural transmission (Vienna, Austria : 1996) · 2014Article
- Inadequate diagnostic evaluation in young patients registered with a diagnosis of dementia: a nationwide register-based study.Dementia and geriatric cognitive disorders extra · 2014Article
- Neurodegenerative disease and obesity: what is the role of weight loss and bariatric interventions?Metabolic brain disease · 2013Review
- Structural and functional brain connectivity in presymptomatic familial frontotemporal dementia.Neurology · 2013Article
- Apolipoprotein Ε ε4 frequency is increased among Chinese patients with frontotemporal dementia and Alzheimer's disease.Dementia and geriatric cognitive disorders · 2013Article
- Neuropsychological and neuroimaging markers in early versus late-onset Alzheimer's disease.American journal of Alzheimer's disease and other dementias · 2012Article
- Nonamnestic presentations of early-onset Alzheimer's disease.American journal of Alzheimer's disease and other dementias · 2012Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Early-onset dementia, presenting before age 65 years, is increasingly recognized. It is often difficult to diagnose, since non-Alzheimer's etiologies and unusual dementias are common. These conditions are more commonly genetic, and important potentially inherited causes of early-onset dementia include early-onset Alzheimer's disease, frontotemporal dementia, Kufs' disease, and Niemann-Pick disease type C. For each of these diseases, this review provides information on common clinical presentations, etiology, pathophysiology, and current and experimental treatments. A discussion of the diagnosis and workup for early-onset dementia is included with an emphasis on conditions that may have other involved family members.
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Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.