ReviewNucleus (Austin, Tex.)
A lamin in lower eukaryotes?
Review in Nucleus (Austin, Tex.). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed, 37 citations in OpenAlex.
- High-resolution map of the Plasmodium falciparum genome reveals MORC/ApiAP2-mediated links between distant, functionally related genes.Nature microbiology · 2025Article
- Structural Diversity and Distribution of Nuclear Matrix Constituent Protein Class Nuclear Lamina Proteins in Streptophytic Algae.Genome biology and evolution · 2024Article
- Lamins as structural nuclear elements through evolution.Current opinion in cell biology · 2023Review
- Cohesin contributes to transcriptional repression of stage-specific genes in the human malaria parasite.EMBO reports · 2023Article
- Looking outside the box: a comparative cross-kingdom view on the cell biology of the three major lineages of eukaryotic multicellular life.Cellular and molecular life sciences : CMLS · 2023Review
- Review
- In Vivo Assembly of aCells · 2020Article
- Exploring the virulence gene interactome with CRISPR/dCas9 in the human malaria parasite.Molecular systems biology · 2020Article
- Nuclear lamina CRWN proteins regulate chromatin organization, gene expression, and nuclear body formation in plants.Journal of plant research · 2020Article
- Unraveling the 3D genome of human malaria parasites.Seminars in cell & developmental biology · 2019Review
- Evolutionary history and structure of nuclear matrix constituent proteins, the plant analogues of lamins.Journal of experimental botany · 2019Article
- Supramolecular Structures of theCells · 2019Article
- Src1 is a Protein of the Inner Nuclear Membrane Interacting with the Dictyostelium Lamin NE81.Cells · 2016Article
- Evolution of the nucleus.Current opinion in cell biology · 2014Review
- The intriguing plant nuclear lamina.Frontiers in plant science · 2014Review
- Nuclear mechanics in cancer.Advances in experimental medicine and biology · 2014Review
- Networking galore: intermediate filaments and cell migration.Current opinion in cell biology · 2013Review
- A ceRNA analysis on LMNA gene focusing on the Hutchinson-Gilford progeria syndrome.Journal of clinical bioinformatics · 2013Article
- NMCP/LINC proteins: putative lamin analogs in plants?Plant signaling & behavior · 2013Review
- Telomeres, tethers and trypanosomes.Nucleus (Austin, Tex.)Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Lamins are the major components of the nuclear lamina and serve not only as a mechanical support, but are also involved in chromatin organization, epigenetic regulation, transcription and mitotic events. Despite these universal tasks, lamins have so far been found only in metazoans. Yet, recently we have identified Dictyostelium NE81 as the first lamin-like protein in a lower eukaryote. Based on the current knowledge, we draw a model for nuclear envelope organization in Dictyostelium in this Extra View and we review the experimental data that justified this classification. Furthermore we provide unpublished data underscoring the requirement of posttranslational CaaX-box processing for proper protein localization at the nuclear envelope. Sequence comparison of NE81 sequences from four Dictyostelia with bona fide lamins illustrates the evolutional relationship between these proteins. Under certain conditions these usually unicellular social amoebae congregate to form a multicellular body. We propose that the evolution of the lamin-like NE81 went along with the invention of multicellularity.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.