ArticleJournal of neurophysiology2012
Intrinsic and synaptic properties of vertical cells of the mouse dorsal cochlear nucleus.
Article in Journal of neurophysiology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed, 42 citations in OpenAlex.
- Effects of Gap Junctions and Inhibition on the Synchronization Behavior of a Biophysically Detailed Neural Network Model of Bushy Cells.Journal of the Association for Research in Otolaryngology : JARO · 2026Article
- Identification and quantification of GABAIBRO neuroscience reports · 2025Article
- Electrophysiological correlates of divergent projections in the avian superior olivary nucleus.Journal of neurophysiology · 2024Article
- The NaeLife · 2024Article
- The NabioRxiv : the preprint server for biology · 2023Article
- Expression and Neurotransmitter Association of the Synaptic Calcium Sensor Synaptotagmin in the Avian Auditory Brain Stem.Journal of the Association for Research in Otolaryngology : JARO · 2022Article
- Descending Axonal Projections from the Inferior Colliculus Target Nearly All Excitatory and Inhibitory Cell Types of the Dorsal Cochlear Nucleus.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2022Article
- Identification of an inhibitory neuron subtype, the L-stellate cell of the cochlear nucleus.eLife · 2020Article
- Classification of neurons in the adult mouse cochlear nucleus: Linear discriminant analysis.PloS one · 2019Article
- A biophysical modelling platform of the cochlear nucleus and other auditory circuits: From channels to networks.Hearing research · 2018Article
- Serotonergic Modulation of Sensory Representation in a Central Multisensory Circuit Is Pathway Specific.Cell reports · 2017Article
- Spontaneous Activity Defines Effective Convergence Ratios in an Inhibitory Circuit.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2016Article
- Altered vesicular glutamate transporter distributions in the mouse cochlear nucleus following cochlear insult.Neuroscience · 2016Article
- Functional organization of the mammalian auditory midbrain.The journal of physiological sciences : JPS · 2015Review
- Tonic zinc inhibits spontaneous firing in dorsal cochlear nucleus principal neurons by enhancing glycinergic neurotransmission.Neurobiology of disease · 2015Article
- Synaptic mechanisms for generating temporal diversity of auditory representation in the dorsal cochlear nucleus.Journal of neurophysiology · 2015Article
- Tonotopic organization of vertical cells in the dorsal cochlear nucleus of the CBA/J mouse.The Journal of comparative neurology · 2014Article
- Cell-type specific short-term plasticity at auditory nerve synapses controls feed-forward inhibition in the dorsal cochlear nucleus.Frontiers in neural circuits · 2014Article
- Projections from the dorsal and ventral cochlear nuclei to the medial geniculate body.Frontiers in neuroanatomy · 2014Article
- Glycinergic synaptic transmission in the cochlear nucleus of mice with normal hearing and age-related hearing loss.Journal of neurophysiology · 2013Article
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3 authors at 1 institution in 1 country.
Funding
Abstract
Multiple classes of inhibitory interneurons shape the activity of principal neurons of the dorsal cochlear nucleus (DCN), a primary target of auditory nerve fibers in the mammalian brain stem. Feedforward inhibition mediated by glycinergic vertical cells (also termed tuberculoventral or corn cells) is thought to contribute importantly to the sound-evoked response properties of principal neurons, but the cellular and synaptic properties that determine how vertical cells function are unclear. We used transgenic mice in which glycinergic neurons express green fluorescent protein (GFP) to target vertical cells for whole cell patch-clamp recordings in acute slices of DCN. We found that vertical cells express diverse intrinsic spiking properties and could fire action potentials at high, sustained spiking rates. Using paired recordings, we directly examined synapses made by vertical cells onto fusiform cells, a primary DCN principal cell type. Vertical cell synapses produced unexpectedly small-amplitude unitary currents in fusiform cells, and additional experiments indicated that multiple vertical cells must be simultaneously active to inhibit fusiform cell spike output. Paired recordings also revealed that a major source of inhibition to vertical cells comes from other vertical cells.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.