ArticleDrug and alcohol dependence2012
Steppingstone and gateway ideas: a discussion of origins, research challenges, and promising lines of research for the future.
Article in Drug and alcohol dependence, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.
- Cannabis use and suicide in people with a diagnosis of schizophrenia: a systematic review and meta-analysis of longitudinal, case control, and cross-sectional studies.Psychological medicine · 2025Pooled it
- Elevated Stress Reactivity: A Barrier to Cannabis Use Change Behavior.Substance use & misuse · 2026Article
- Persistence of extra-medical prescription pain reliever use and alcohol involvement among United States 12-20 year olds.Experimental and clinical psychopharmacology · 2019Article
- Does Starting to Smoke Cigars Trigger Onset of Cannabis Blunt Smoking?Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2018Article
- Gene variants and educational attainment in cannabis use: mediating role of DNA methylation.Translational psychiatry · 2018Article
- Nonmedical prescription opioids and pathways of drug involvement in the US: Generational differences.Drug and alcohol dependence · 2018Article
- Longitudinal Studies on the Etiology of Cannabis Use Disorder: A Review.Current addiction reports · 2017Article
- Obsolete tobacco control themes can be hazardous to public health: the need for updating views on absolute product risks and harm reduction.BMC public health · 2016Article
- Age of Sexual Debut and Cannabis Use in the United States.Substance use & misuse · 2016Article
- The therapeutic potential of cannabinoids for movement disorders.Movement disorders : official journal of the Movement Disorder Society · 2015Review
- Cannabis controversies: how genetics can inform the study of comorbidity.Addiction (Abingdon, England) · 2014Review
- Marijuana: current concepts(†).Frontiers in public health · 2013Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
Abstract
In this discussion of contributed papers for the special issue of DAD, the author draws attention to early American laws concerning cannabis and to statements made about the epidemiology of cannabis smoking and other drug use between 1858 and the contemporary scene, with coverage of opium, heroin, tobacco, alcohol, cocaine, kava, and other drugs. He discusses these steppingstone and gateway processes in relation to political environment and in relation to scientific challenges such as uncontrolled confounding. He provides a critique of between-individual research designs, including co-twin and co-sib designs of behavior genetics, as well as imaging research, where uncontrolled confounding often exists. He highlights the epidemiologic case-crossover design and prevention research experiments as potentially valuable approaches in new directions for research on the steppingstone and gateway processes.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.