Evidence map›Paper›PMID 22571920›Full record

ArticleAddictive behaviors2012

Differential cigarette-related startle cue reactivity among light, moderate, and heavy smokers.

Yong Cui, Jason D Robinson, Francesco Versace, Cho Y Lam, Jennifer A Minnix, Maher Karam-Hage, John A Dani, Thomas R Kosten, David W Wetter, Victoria L Brown and 1 more

Registry-linked trialAbstract read
In one paragraph

Article in Addictive behaviors, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00507728 (Pharmacogenetics, Emotional Reactivity and Smoking), which is not on this map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00507728 phase2 / phase3completednot on this map

Pharmacogenetics, Emotional Reactivity and Smoking

TypeinterventionalSponsorM.D. Anderson Cancer CenterRan2005 to 2019Enrolled646ConditionsTobacco Use Disorder, Smoking CessationArmsBupropion, Varenicline, Placebo, Smoking Cessation Counseling
3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Pharmacological intervention and abstinence in smokers undergoing cessation treatment: A psychophysiological study.International journal of psychophysiology : official journal of the International Organization of Psychophysiology · 2018
    Trial
  2. Randomized trial of telephone-delivered acceptance and commitment therapy versus cognitive behavioral therapy for smoking cessation: a pilot study.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2014
    Trial
  3. Article
  4. Article
  5. The impact of nicotine dose and instructed dose on smokers' implicit attitudes to smoking cues: An ERP study.Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2019
    Article
  6. Article
  7. Alpha oscillations in response to affective and cigarette-related stimuli in smokers.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2013
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Yong CuiGraduate Program in Translational Biology and Molecular Medicine, Baylor College of Medicine, USA.
Jason D Robinson
Francesco Versace
Cho Y Lam
Jennifer A Minnix
Maher Karam-Hage
John A Dani
Thomas R Kosten
David W Wetter
Victoria L Brown
Paul M Cinciripini

Funding

Tumor Evolution and Metastasis ProgramP30CA016672 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI DIANE BODURKA · 1985 to 2026
$290.8M
Pharmacogenetics, Emotional Reactivity &Smoking(RMI)R01DA017073 · NIDA · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI CINCIRIPINI, PAUL MICHAEL · 2004 to 2009
$3.0M
NCI NIH HHS CA016672NCI NIH HHS P30 CA016672NIDA NIH HHS R01 DA017073NIDA NIH HHS R01DA017073
6 · The paper itself

Abstract

In this study, we examined the relationship between the level of daily cigarette consumption and the startle response to affective and cigarette-related cues among treatment-seeking smokers. Before receiving any behavioral or pharmacological treatment, 136 smokers attended a baseline laboratory session, during which we recorded their reflexive eyeblink responses to acoustic startle probes while they were viewing pleasant, unpleasant, neutral, and cigarette-related pictures. We found that 1) cigarette-related and pleasant pictures similarly reduced the startle magnitude compared to neutral pictures; 2) the magnitude of startle modulation rendered by pleasant or unpleasant pictures did not differ among light, moderate, and heavy smokers; and 3) startle attenuation by cigarette-related pictures was greater in heavy smokers than in light smokers. These results suggest that similar to pleasant stimuli, cigarette-related cues are motivationally salient for smokers, and that this salience increases with nicotine dependence.

Indexed as

AdolescentAdultAgedBlinkingCuesFemaleHumansMaleMiddle AgedReflex, StartleSmokingSmoking CessationTexasYoung Adult

Identifiers

PMID22571920
PMCPMC3358408

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.