ArticleJournal of investigative surgery : the official journal of the Academy of Surgical Research2012
Impact of hepatic arterial reconstruction on orthotopic liver transplantation in the rat.
Article in Journal of investigative surgery : the official journal of the Academy of Surgical Research, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 14 citations in OpenAlex.
- Dual drug targeting to kill colon cancers.Cancer medicine · 2022Article
- Protection of liver sinusoids by intravenous administration of human Muse cells in a rat extra-small partial liver transplantation model.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2021Article
- The Impact of Biliary Reconstruction Methods on Small Partial Liver Grafts.Transplantation direct · 2020Article
- A novel model forIslets · 2019Article
- Management of early hepatic artery occlusion after liver transplantation with failed rescue.World journal of gastroenterology · 2015Review
- Gene silencing of 4-1BB by RNA interference inhibits acute rejection in rats with liver transplantation.BioMed research international · 2013Article
- Article
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Authors and funding
7 authors at 3 institutions in 2 countries.
Funding
Abstract
Orthotopic liver transplantation (OLT) models in rats have been investigated in many studies, but detailed information on the impact of hepatic artery (HA) reconstruction on postoperative factors remains to be investigated. HA reconstruction also requires advanced skills. The effect of the reconstruction of the HA by a hand-suture technique in rats with a whole-liver syngeneic graft was investigated. Long-term survival, histopathological assessment, immunohistological evaluation, and blood biochemistry were investigated until postoperative day (POD) 28. From the early postoperative period, significant differences between OLTs with or without HA reconstruction were found in graft parenchymal damage, induction of apoptosis, and transaminase levels, though survival curves and the coagulation profile showed no differences. In OLT without HA reconstruction, biliary proliferation was decreased at POD 5-14, and total bilirubin level was increased at PODs 10 and 14. The study indicates that HA reconstruction is required for reliable OLT in rats.
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