Evidence map›Paper›PMID 22570672›Full record

ArticleEvidence-based complementary and alternative medicine : eCAM2012

Sino-European transcontinental basic and clinical high-tech acupuncture studies-part 3: violet laser stimulation in anesthetized rats.

Xin-Yan Gao, Gerhard Litscher, Kun Liu, Bing Zhu

Abstract read
In one paragraph

Article in Evidence-based complementary and alternative medicine : eCAM, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. The Application of Laser Acupuncture in Animal Experiments: A Narrative Review of Biological Aspects.Evidence-based complementary and alternative medicine : eCAM · 2021
    Review
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Auricular acupuncture with laser.Evidence-based complementary and alternative medicine : eCAM · 2013
    Article
  9. Article
  10. Article
  11. Stimulation of TRPV1 by Green Laser Light.Evidence-based complementary and alternative medicine : eCAM · 2012
    Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Xin-Yan GaoStronach Research Unit for Complementary and Integrative Laser Medicine, Research Unit of Biomedical Engineering in Anesthesia and Intensive Care Medicine, TCM Research Center Graz, Medical University of Graz, Auenbruggerplatz 29, 8036 Graz, Austria.
Gerhard Litscher
Kun Liu
Bing Zhu

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this study was to determine the effect of violet laser stimulation on three acupuncture points in anesthetized rats and to test the hypothesis that violet laser light can modulate neurovegetative parameters like heart rate (HR), heart rate variability (HRV), and mean arterial blood pressure (MAP). Recordings were performed in 10 male anesthetized rats under three conditions in Beijing, and monitored with equipment from Graz, where also data analysis was performed. For stimulation a violet laser (emitted wavelength 405 nm, laser output 1 mW, continuous mode) was used. The electrocardiograms were recorded by an HRV Medilog AR12 system during laser acupuncture stimulation of the head, ear, and body (Baihui, "heart" ear acupoint, Zusanli). HR changed significantly only during (P = 0.013) and after (P = 0.038) stimulation at Baihui. Total HRV and the low frequency/high frequency ratio showed insignificant changes. There was an insignificant decrease in MAP after stimulation of Baihui acupoint. Violet laser stimulation offers a method to induce acute effects in HR and HRV in rats. Although the precise mechanism of this effect remains to be determined, alterations are significant. Violet laser stimulation on the Baihui acupoint could readily be translated to clinical studies.

Identifiers

PMID22570672
PMCPMC3337607

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.