Evidence map›Paper›PMID 22570529›Full record

ReviewJournal of biomedicine & biotechnology2012

Molecular imaging in tracking tumor stem-like cells.

Tian Xia, Han Jiang, Chenrui Li, Mei Tian, Hong Zhang

Open access · hybridAbstract readReview
In one paragraph

Review in Journal of biomedicine & biotechnology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Article
  3. Frontiers in bioengineering and biotechnology · 2022
    Article
  4. Article
  5. Experimental and therapeutic medicine · 2018
    Article
  6. Article
  7. Review
  8. Article
  9. Technology advancement for integrative stem cell analyses.Tissue engineering. Part B, Reviews · 2014
    Review
  10. Cancer stem cell theory and the warburg effect, two sides of the same coin?International journal of molecular sciences · 2014
    Article
  11. Noninvasive positron emission tomography and fluorescence imaging of CD133+ tumor stem cells.Proceedings of the National Academy of Sciences of the United States of America · 2014
    Article
  12. [Identification and isolation of cancer stem cells from A549 cells].Zhongguo fei ai za zhi = Chinese journal of lung cancer · 2013
    Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

Tian XiaDepartment of Nuclear Medicine, Second Affiliated Hospital of Zhejiang University, School of Medicine, Hangzhou, Zhejiang , China.
Han Jiang
Chenrui Li
Mei Tian
Hong Zhang
Second Affiliated Hospital of Zhejiang University · CNChinese University of Hong Kong · CNZhejiang Chinese Medical University · CNZhejiang University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cancer remains a major public health problem in many countries. It was found to contain a subset of cancer stem cells (CSCs) that are capable of proliferation and self-renewal, and differentiation into various types of cancer cells. CSCs often display characteristics of chemotherapy resistance and radiotherapy resistance. Numerous putative biomarkers of CSCs are currently identified including CD133, CD44, CD24, ALDH (aldehyde dehydrogenase), and ABCG2. Interestingly, no single marker is exclusively expressed by CSCs. Thus, the various combinations of different biomarkers will be possible to identify CSCs, and considerable work is being done to recognize new ones. In order to demonstrate the mechanisms of resistance and response to therapy and predict the outcome as well as prognosis, the ways to track and identify CSCs will be extremely important. The technologies of molecular imaging will reveal mechanisms of cancer progression and provide visual targets for novel therapeutics. Limited studies were investigated on the detection of various types of CSCs by molecular imaging. Although the tracking of circulating CSCs is still hampered by technological challenges, personalized diagnosis and therapies of cancers are expected to be established based on increased understanding of molecular imaging of cancer stem-like cells biomarkers.

Indexed as

AnimalsBiomarkers, TumorCell TrackingHumansMiceMolecular ImagingNeoplasmsNeoplastic Stem CellsBiomarkers, Tumor

Identifiers

PMID22570529
PMCPMC3335324
OpenAlexW2079494400

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.