ArticleAnnals of intensive care2012
Near infrared spectroscopy (NIRS) of the thenar eminence in anesthesia and intensive care.
Article in Annals of intensive care, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
38 citing papers in PubMed, 105 citations in OpenAlex.
- Near-infrared spectroscopy for assessing microcirculation during laparoscopic gynaecological surgery under combined spinal-general anaesthesia or general anaesthesia alone: a randomised controlled trial.Journal of clinical monitoring and computing · 2020Trial
- Enhanced accuracy of NIRS-vascular occlusion testing through incorporation of conduit artery diameter.JPhys photonics · 2026Article
- "hDOS": an automated hybrid diffuse optical device for real-time noninvasive tissue monitoring: precision andJournal of biomedical optics · 2025Article
- Quantitative analysis of tissue oxygenation variability across anatomical landmarks in healthy individuals via near-infrared spectroscopy.Scientific reports · 2025Article
- Albumin Enhances Microvascular Reactivity in Sepsis: Insights from Near-Infrared Spectroscopy and Vascular Occlusion Testing.Journal of clinical medicine · 2025Article
- Foundations and Advancements in Hemodynamic Monitoring: Part I-Elements of HemodynamicsTurkish journal of anaesthesiology and reanimation · 2025Article
- Article
- Near-Infrared Spectroscopy (NIRS) to Assess Infection Complications During the Acute Phase of Acute Pancreatitis.Diagnostics (Basel, Switzerland) · 2024Article
- Non-invasive assessment of sublingual microcirculation using flow derived from green light PPG: evaluation and reference values.Journal of biomedical optics · 2024Article
- Assessment of power spectral density of microvascular hemodynamics in skeletal muscles at very low and low-frequency via near-infrared diffuse optical spectroscopies.Biomedical optics express · 2023Article
- Agreement of somatic and renal near-infrared spectroscopy with reference blood samples during a controlled hypoxia sequence: a healthy volunteer study.Journal of clinical monitoring and computing · 2023Article
- Near-Infrared Spectroscopy for Determination of Cardiac Output Augmentation in a Swine Model of Ischemia-Reperfusion Injury.Critical care explorations · 2022Article
- Altered microvascular reactivity assessed by near-infrared spectroscopy after hepato-pancreato-biliary surgery.Journal of clinical monitoring and computing · 2022Observational
- Predicting the Need for Renal Replacement Therapy Using a Vascular Occlusion Test and Tissue Oxygen Saturation in Patients in the Early Phase of Multiorgan Dysfunction Syndrome.Journal of clinical medicine · 2022Article
- Performance Assessment of a Commercial Continuous-Wave Near-Infrared Spectroscopy Tissue Oximeter for Suitability for Use in an International, Multi-Center Clinical Trial.Sensors (Basel, Switzerland) · 2021Article
- The vascular occlusion test using multispectral imaging: a validation study : The VASOIMAGE study.Journal of clinical monitoring and computing · 2021Article
- Assessment of sublingual microcirculation in critically ill patients: consensus and debate.Annals of translational medicine · 2020Review
- Tissue oxygen saturation changes and postoperative complications in cardiac surgery: a prospective observational study.BMC anesthesiology · 2019Observational
- A Spectral Filter Array Camera for Clinical Monitoring and Diagnosis: Proof of Concept for Skin Oxygenation Imaging.Journal of imaging · 2019Article
- Journal of Clinical Monitoring and Computing 2017/2018 end of year summary: monitoring-and provocation-of the microcirculation and tissue oxygenation.Journal of clinical monitoring and computing · 2019Review
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Near infrared spectroscopy of the thenar eminence (NIRSth) is a noninvasive bedside method for assessing tissue oxygenation. The NIRS probe emits light with several wavelengths in the 700- to 850-nm interval and measures the reflected light mainly from a predefined depth. Complex physical models then allow the measurement of the relative concentrations of oxy and deoxyhemoglobin, and thus tissue saturation (StO2), as well as an approximation of the tissue hemoglobin, given as tissue hemoglobin index.Here we review of current knowledge of the application of NIRSth in anesthesia and intensive care.We performed an analytical and descriptive review of the literature using the terms "near-infrared spectroscopy" combined with "anesthesia," "anesthesiology," "intensive care," "critical care," "sepsis," "bleeding," "hemorrhage," "surgery," and "trauma" with particular focus on all NIRS studies involving measurement at the thenar eminence.We found that NIRSth has been applied as clinical research tool to perform both static and dynamic assessment of StO2. Specifically, a vascular occlusion test (VOT) with a pressure cuff can be used to provide a dynamic assessment of the tissue oxygenation response to ischemia. StO2 changes during such induced ischemia-reperfusion yield information on oxygen consumption and microvasculatory reactivity. Some evidence suggests that StO2 during VOT can detect fluid responsiveness during surgery. In hypovolemic shock, StO2 can help to predict outcome, but not in septic shock. In contrast, NIRS parameters during VOT increase the diagnostic and prognostic accuracy in both hypovolemic and septic shock. Minimal data are available on static or dynamic StO2 used to guide therapy.Although the available data are promising, further studies are necessary before NIRSth can become part of routine clinical practice.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.