ArticleObesity (Silver Spring, Md.)2012
Brain response to food stimulation in obese, normal weight, and successful weight loss maintainers.
Article in Obesity (Silver Spring, Md.), 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed.
- Brain reactivity to visual food stimuli after moderate-intensity exercise in children.Brain imaging and behavior · 2018Trial
- Preference for ugly faces? -A cognitive study of attentional and memorial biases toward facial information among young females with facial dissatisfaction.Frontiers in psychology · 2022Article
- Reversal of Functional Brain Activity Related to Gut Microbiome and Hormones After VSG Surgery in Patients With Obesity.The Journal of clinical endocrinology and metabolism · 2021Observational
- The Role of the Human Hypothalamus in Food Intake Networks: An MRI Perspective.Frontiers in nutrition · 2021Review
- Genetic variation affects binge feeding behavior in female inbred mouse strains.Scientific reports · 2019Article
- Machine Learning Based Classification of Resting-State fMRI Features Exemplified by Metabolic State (Hunger/Satiety).Frontiers in human neuroscience · 2019Article
- Weight Loss Maintenance: Have We Missed the Brain?Brain sciences · 2018Review
- Nucleus accumbens inflammation mediates anxiodepressive behavior and compulsive sucrose seeking elicited by saturated dietary fat.Molecular metabolism · 2018Article
- Food Cue Reactivity and the Brain-Heart Axis During Cognitive Stress Following Clinically Relevant Weight Loss.Frontiers in nutrition · 2018Article
- Weight Loss and Appetite Control in Women.Current obesity reports · 2017Review
- Prefrontal gray matter volume mediates genetic risks for obesity.Molecular psychiatry · 2017Article
- Effects of the modern food environment on striatal function, cognition and regulation of ingestive behavior.Current opinion in behavioral sciences · 2016Article
- Differential effects of hunger and satiety on insular cortex and hypothalamic functional connectivity.The European journal of neuroscience · 2016Article
- Brain imaging demonstrates a reduced neural impact of eating in obesity.Obesity (Silver Spring, Md.) · 2016Article
- Appetite and body weight regulation after bariatric surgery.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2015Review
- A Cognitive Profile of Obesity and Its Translation into New Interventions.Frontiers in psychology · 2015Article
- Is it Worth the Effort? Novel Insights into Obesity-Associated Alterations in Cost-Benefit Decision-Making.Frontiers in behavioral neuroscience · 2015Article
- NIH working group report: Innovative research to improve maintenance of weight loss.Obesity (Silver Spring, Md.) · 2015Review
- Differences in the neuronal response to food in obesity-resistant as compared to obesity-prone individuals.Physiology & behavior · 2013Article
- Food related processes in the insular cortex.Frontiers in human neuroscience · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
Abstract
As many people struggle with maintenance of weight loss, the study of successful weight loss maintainers (SWLM) can yield important insights into factors contributing to weight loss maintenance. However, little research has examined how SWLM differ from people who are obese or normal weight (NW) in brain response to orosensory stimulation. The goal of this study was to determine if SWLM exhibit different brain responses to orosensory stimulation. Brain response to 1-min orosensory stimulation with a lemon lollipop was assessed using functional magnetic resonance imaging among 49 participants, including SWLM (n = 17), NW (n = 18), and obese (n = 14) controls. Significant brain responses were observed in nine brain regions, including the bilateral insula, left inferior frontal gyrus, left putamen, and other sensory regions. All regions also exhibited significant attenuation of this response over 1 min. The SWLM exhibited greater response compared with the other groups in all brain regions. Findings suggest that the response to orosensory stimulation peaks within 40 s and attenuates significantly between 40 and 60 s in regions associated with sensation, reward, and inhibitory control. Greater reactivity among the SWLM suggests that greater sensory reactivity to orosensory stimulation, increased anticipated reward, and subsequently greater inhibitory processing are associated with weight loss maintenance.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.