ArticleCritical care (London, England)2012
Obese trauma patients are at increased risk of early hypovolemic shock: a retrospective cohort analysis of 1,084 severely injured patients.
Article in Critical care (London, England), 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
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Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it, 62 citations in OpenAlex.
- Care of patients with obesity in the Emergency Department: a joint position statement from the Brazilian Association of Emergency Medicine (ABRAMEDE) and the Brazilian Association for the Study of Obesity and Metabolic Syndrome (ABESO).Archives of endocrinology and metabolism · 2025Guideline
- Article
- Obesity: a challenge for emergency medical teams-a narrative review.Frontiers in public health · 2025Review
- Fibrinogen Inhibits Metalloproteinase-9 Activation and Syndecan-1 Cleavage to Protect Lung Function in ApoE Null Mice After Hemorrhagic Shock.The Journal of surgical research · 2023Article
- Subcutaneous Adipose Tissue Is Associated with Acute Kidney Injury after Abdominal Trauma Based on the Generalized Propensity Score Approach: A Retrospective Cohort Study.Obesity facts · 2023Article
- Emergencies in obese patients: a narrative review.Journal of anesthesia, analgesia and critical care · 2021Review
- Impact of pathologic body composition assessed by CT-based anthropometric measurements in adult patients with multiple trauma: a retrospective analysis.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2021Article
- The effect of perturbations of the glycocalyx on microvascular perfusion in the obese trauma population: an in vitro study.Trauma surgery & acute care open · 2021Article
- Relationship of body mass index, serum creatine kinase, and acute kidney injury after severe trauma.The journal of trauma and acute care surgery · 2020Article
- Obesity in the critically ill: a narrative review.Intensive care medicine · 2019Review
- The impact of body mass index on resource utilization and outcomes of children admitted to a pediatric intensive care unit.SAGE open medicine · 2019Article
- Process Mining the Trauma Resuscitation Patient Cohorts.Proceedings. IEEE International Conference on Healthcare Informatics · 2018Article
- Diet-Induced Obesity Affects Muscle Regeneration After Murine Blunt Muscle Trauma-A Broad Spectrum Analysis.Frontiers in physiology · 2018Article
- Complications of pelvic and acetabular fractures in 1331 morbidly obese patients (BMI ≥ 40): a retrospective observational study from the National Trauma Data Bank.Patient safety in surgery · 2018Article
- Trauma and BMI Mortality.Current obesity reports · 2017Review
- OBESITY AND CRITICAL ILLNESS: INSIGHTS FROM ANIMAL MODELS.Shock (Augusta, Ga.) · 2016Review
- Observational
- Theoretical Analysis of the Relative Impact of Obesity on Hemodynamic Stability During Acute Hemorrhagic Shock.Archives of trauma research · 2015Article
- β2-adrenergic regulation of stress hyperglycemia following hemorrhage in the obese Zucker rat.Physiological reports · 2014Article
- Physiological and management implications of obesity in critical illness.Annals of the American Thoracic Society · 2014Review
Corrections and comments
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Authors and funding
7 authors at 7 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionMorbid obesity and its consequences are considered risk factors for adverse outcome in trauma, although the pathophysiologic mechanisms are incompletely understood. The aim of this study was to compare initial resuscitation, treatment, and short-term outcome of severely injured patients by body mass index (BMI).
methodsA total of 1,084 severely injured patients with an injury severity score of 16 or greater were enrolled between 1996 and 2009 and grouped according to BMI. Their course of treatment and in-hospital outcome were analyzed by univariate and multivariate comparison.
resultsOf these patients, 603 (55.6%) were of normal weight with a BMI between 18.5 and 24.9, 361 (33.3%) had BMI values between 25 and 29.9, and 90 patients (8.3%) were obese (BMI ≥ 30). Thirty patients (2.8%) had BMI levels below 18.5. All groups were comparable with respect to injury severity, initial resuscitation, and time to ICU admission. There was a tendency towards higher mortality in obese patients (mortality 24.4%) and also overweight patients (mortality 18.8%) when compared with patients with a normal BMI (mortality 16.6%). Obese patients showed the highest mortality on day 0 (8.9% vs. 2.8% in the normal-weight group, P = 0.023), mostly due to persistent shock (6.7%). When corrected for BMI, obese patients are provided significantly lower volumes of intravenous fluids during the initial resuscitation period.
conclusionIn contrast to the mostly American literature, only a low percentage of trauma patients at a European trauma center are obese. These patients are at risk of higher mortality from persistent hemorrhagic shock in the initial phase after trauma, which may potentially be related to relative hypovolemia during the resuscitation period. In the later course of treatment, no significant differences exist with respect to specific complications, hospital stay, or in-hospital mortality.
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