ArticleOrganic letters2012
A phosphate tether-mediated, one-pot, sequential ring-closing metathesis/cross-metathesis/chemoselective hydrogenation protocol.
Article in Organic letters, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed.
- Synthesis of Simplified 2-Desmethyl Sanctolide A Analogs.The Journal of organic chemistry · 2024Article
- Total Synthesis of Sanctolide A and Formal Synthesis of (2The Journal of organic chemistry · 2023Article
- P-Stereogenic Bicyclo[4.3.1]phosphite Boranes: Synthesis and Utility of Tunable P-Tether Systems for the Desymmetrization of COrganic letters · 2017Article
- P-Tether-Mediated, Iterative SOrganic letters · 2017Article
- Modular Synthesis of Novel Macrocycles Bearing α,β-Unsaturated Chemotypes through a Series of One-Pot, Sequential Protocols.Chemistry (Weinheim an der Bergstrasse, Germany) · 2016Article
- Total Synthesis of Cryptocaryol A by Enantioselective Iridium-Catalyzed Alcohol C-H Allylation.Angewandte Chemie (International ed. in English) · 2016Article
- A Pot-Economical Approach to the Total Synthesis of Sch-725674.Organic letters · 2016Article
- Synthetic Studies to Lyngbouilloside: A Phosphate Tether-Mediated Synthesis of the Macrolactone Core.Tetrahedron letters · 2015Article
- An efficient, modular approach for the synthesis of (+)-strictifolione and a related natural product.Organic letters · 2014Article
- A modular phosphate tether-mediated divergent strategy to complex polyols.Beilstein journal of organic chemistry · 2014Article
- Phosphate-tether-mediated ring-closing metathesis for the preparation of complex 1,3-anti-diol-containing subunits.Chemistry (Weinheim an der Bergstrasse, Germany) · 2013Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
A versatile three-step, one-pot, sequential reaction protocol involving ring-closing metathesis, cross-metathesis, and chemoselective hydrogenation is reported. This phosphate tether-mediated process occurs without intermediate isolation, is chemoselective, and is governed by stereoelectronic properties innate to phosphate tethers, which ultimately act to preserve the integrity of the bisallylic, bicyclic phosphate for subsequent nucleophilic additions. Overall, this process can be used to efficiently generate advanced polyol synthons.
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Registered trials
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