Evidence map›Paper›PMID 22567598›Full record

ArticleBiomedical optics express2012

Scattering phase function spectrum makes reflectance spectrum measured from Intralipid phantoms and tissue sensitive to the device detection geometry.

S C Kanick, V Krishnaswamy, U A Gamm, H J C M Sterenborg, D J Robinson, A Amelink, B W Pogue

Abstract read
In one paragraph

Article in Biomedical optics express, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

S C Kanick
V Krishnaswamy
U A Gamm
H J C M Sterenborg
D J Robinson
A Amelink
B W Pogue

Funding

Small Molecule Enhancers of Photodynamic Therapy for Skin CancerP01CA084203 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI Bryan Quilty Spring · 2001 to 2026
$27.9M
Near Infrared Spectroscopy and ImagingP01CA080139 · NCI · DARTMOUTH COLLEGE · PI POPLACK, STEVEN P · 1999 to 2010
$13.6M
Toxicology, Pathology and Biodistribution Core (TPB Core)U54CA151662 · NCI · DARTMOUTH COLLEGE · PI POGUE, BRIAN WILLIAM · 2010 to 2014
$11.6M
NCI NIH HHS P01 CA080139NCI NIH HHS P01 CA084203NCI NIH HHS U54 CA151662
6 · The paper itself

Abstract

Reflectance spectra measured in Intralipid (IL) close to the source are sensitive to wavelength-dependent changes in reduced scattering coefficient ([Formula: see text]) and scattering phase function (PF). Experiments and simulations were performed using device designs with either single or separate optical fibers for delivery and collection of light in varying concentrations of IL. Spectral reflectance is not consistently linear with varying IL concentration, with PF-dependent effects observed for single fiber devices with diameters smaller than ten transport lengths and for separate source-detector devices that collected light at less than half of a transport length from the source. Similar effects are thought to be seen in tissue, limiting the ability to quantitatively compare spectra from different devices without compensation.

Indexed as

(170.3660) Light propagation in tissues(170.6510) Spectroscopy, tissue diagnostics(170.7050) Turbid media

Identifiers

PMID22567598
PMCPMC3342184

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.