ArticleGenetics research international2012
The molecular biology of vestibular schwannomas and its association with hearing loss: a review.
Article in Genetics research international, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
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Who cites it
12 citing papers in PubMed, 31 citations in OpenAlex.
- Hearing loss and vestibular schwannoma: new insights into Schwann cells implication.Cell death & disease · 2023Review
- Multiplatform molecular analysis of vestibular schwannoma reveals two robust subgroups with distinct microenvironment.Journal of neuro-oncology · 2023Article
- Immunological Analysis of Vestibular Schwannoma Patients.The journal of international advanced otology · 2023Article
- Long non-coding RNA BRCAT54 sponges microRNA-21 in vestibular schwannoma to suppress cell proliferation.Bioengineered · 2022Article
- Genomics, Epigenetics, and Hearing Loss in Neurofibromatosis Type 2.Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology · 2020Review
- Biomarkers in Vestibular Schwannoma-Associated Hearing Loss.Frontiers in neurology · 2019Review
- Upregulation of microRNA 344a-3p is involved in curcumin induced apoptosis in RT4 schwannoma cells.Cancer cell international · 2018Article
- Microarray Expression Data Identify DCC as a Candidate Gene for Early Meningioma Progression.PloS one · 2016Article
- Merlin, the NF2 gene product.Pathology oncology research : POR · 2013Review
- Recurrent schwannoma postirradiation: histological review reveals mixed schwannoma and meningioma.Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery · 2013Article
- Frequency of loss of heterozygosity of the NF2 gene in schwannomas from Croatian patients.Croatian medical journal · 2012Article
- Spontaneous cellular senescence and stress response heterogeneity in human vestibular schwannomas.Neuro-oncology advancesArticle
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Hearing loss is the most common symptom in patients with vestibular schwannoma (VS). In the past, compressive mechanisms caused by the tumoral mass and its growth have been regarded as the most likely causes of the hearing loss associated with VS. Interestingly, new evidence proposes molecular mechanisms as an explanation for such hearing loss. Among the molecular mechanisms proposed are methylation of TP73, negative expression of cyclin D1, expression of B7-H1, increased expression of the platelet-derived growth factor A, underexpression of PEX5L, RAD54B, and PSMAL, and overexpression of CEA. Many molecular mechanisms are involved in vestibular schwannoma development; we review some of these mechanisms with special emphasis on hearing loss associated with vestibular schwannoma.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.