Evidence map›Paper›PMID 22567334›Full record

ArticleJournal of pathogens2011

Characterization of Virulence Factors of Staphylococcus aureus: Novel Function of Known Virulence Factors That Are Implicated in Activation of Airway Epithelial Proinflammatory Response.

Justyna Bien, Olga Sokolova, Przemyslaw Bozko

Open access · hybridAbstract read
In one paragraph

Article in Journal of pathogens, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 65 papers.

0numbers the graph read from it
0cells of the map it votes in
65citing papers in PubMed
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

65 citing papers in PubMed, 166 citations in OpenAlex.

  1. Article
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  4. Review
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  8. DecipheringmSystems · 2024
    Article
  9. Article
  10. Article
  11. Spectrum of Virulence Factors in Clinical Isolates ofJournal of laboratory physicians · 2023
    Article
  12. The Prevalence of the Virulence Genes ofAntibiotics (Basel, Switzerland) · 2023
    Article
  13. Review
  14. Article
  15. Article
  16. Vancomycin Resistance inMicroorganisms · 2022
    Review
  17. The Relative ofArchives of Razi Institute · 2022
    Article
  18. Article
  19. Article
  20. Article

5 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 2 countries.

Justyna BienWitold Stefanski Institute of Parasitology of the Polish Academy of Sciences, Twarda Street 51/55, 00-818 Warsaw, Poland.
Olga Sokolova
Przemyslaw Bozko
Medizinische Hochschule Hannover · DEOtto-von-Guericke University Magdeburg · DEPolish Academy of Sciences · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Airway epithelial cells play a major role in initiating inflammation in response to bacterial pathogens. S. aureus is an important pathogen associated with activation of diverse types of infection characterized by inflammation dominated by polymorphonuclear leukocytes. This bacterium frequently causes lung infection, which is attributed to virulence factors. Many of virulence determinants associated with S. aureus-mediated lung infection have been known for several years. In this paper, we discuss recent advances in our understanding of known virulence factors implicated in pneumonia. We anticipate that better understanding of novel functions of known virulence factors could open the way to regulate inflammatory reactions of the epithelium and to develop effective strategies to treat S. aureus-induced airway diseases.

Identifiers

PMID22567334
PMCPMC3335658
OpenAlexW2161946724

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.