Evidence map›Paper›PMID 22566826›Full record

ArticleFrontiers in immunology2011

CD161-expressing human T cells.

Joannah R Fergusson, Vicki M Fleming, Paul Klenerman

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 75 papers.

0numbers the graph read from it
0cells of the map it votes in
75citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

75 citing papers in PubMed, 117 citations in OpenAlex.

  1. Trial
  2. Review
  3. Article
  4. Article
  5. Circulating TFH2 Cell Expansion and GZMKJournal of asthma and allergy · 2026
    Article
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  10. Review
  11. Review
  12. Oligoclonal CD4Communications biology · 2024
    Article
  13. Journal of thoracic disease · 2024
    Article
  14. Article
  15. Article
  16. Investigating Vα7.2International journal of molecular sciences · 2024
    Article
  17. Article
  18. Article
  19. Article
  20. Article

15 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Joannah R FergussonSir William Dunn School of Pathology, University of Oxford Oxford, UK. joannah.fergusson@ path.ox.ac.uk
Vicki M Fleming
Paul Klenerman
University of Oxford · GB

Funding

Virology CoreU19AI082630 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI RAYMOND T CHUNG, GEORG Michael LAUER · 2009 to 2026
$48.1M
NIAID NIH HHS U19 AI082630
6 · The paper itself

Abstract

Expression of the Natural Killer cell receptor CD161 has recently been identified on a subset of T cells, including both CD4+ T helper and CD8+ T cells. Expression of this molecule within the adult circulation is restricted to those T cells with a memory phenotype. However, the distinct properties of these T cell populations is yet to be fully determined, although expression of CD161 has been related to the secretion of interleukin-17, and therefore to a type 17 phenotype. Recent studies have aimed to determine both the origin of these cells and the significance of CD161 expression as either a marker of specific cell types or as an effector and regulator of lymphocyte function, and hence to characterize the role of these CD161+ cells within a variety of human diseases in which they have been implicated.

Indexed as

CD161interleukin-17NK cellsNKRP1NK-T cellsT cellsT helper 17 cells

Identifiers

PMID22566826
PMCPMC3342360
OpenAlexW2059971670

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.