ArticleAnnals of Indian Academy of Neurology2012
The adolescent or adult with generalized tonic-clonic seizures.
Article in Annals of Indian Academy of Neurology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
10 citing papers in PubMed, 13 citations in OpenAlex.
- Changes in routine blood parameters of patients with generalized tonic clonic seizure: a retrospective study.Neurosciences (Riyadh, Saudi Arabia) · 2023Article
- Article
- Automatic Recognition of High-Density Epileptic EEG Using Support Vector Machine and Gradient-Boosting Decision Tree.Brain sciences · 2022Article
- Article
- The use of virtual tools in narrowing the impact of health disparities in neurology.Frontiers in pediatrics · 2022Article
- Prevalence, Demographic Profile, and Psychological Aspects of Epilepsy in North-Western India: A Community-Based Observational Study.Annals of neurosciences · 2018Article
- Perampanel: A Review in Drug-Resistant Epilepsy.Drugs · 2015Review
- Effect of experimentally induced hepatic and renal failure on the pharmacokinetics of topiramate in rats.BioMed research international · 2014Article
- A Scoring Framework and Apparatus for Epilepsy Seizure Detection Using a Wearable Belt.Journal of medical signals and sensorsArticle
- Alcohol dependent and GTCS patient with sleep-related hyper motor epilepsy.Industrial psychiatry journalArticle
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Primary and secondary generalized tonic-clonic seizures (GTCs) together constitute up to 50% of adolescent and adult patients with epilepsy as diagnosed by history and EEG. Syncope and psychogenic nonepileptic seizures are major differential diagnoses and must be carefully excluded in therapy-resistant cases. Individual episodes can have up to seven phases in secondarily generalized GTCs. The distinction between primary and secondary GTCs depends mainly on history and EEG, and yield can be improved with sleep deprivation or overnight recording. Epilepsies with primary or unclassified GTCs can respond to any one of the five broad-spectrum antiepileptic drugs (AEDs): valproate, lamotrigine, levetiracetam, topiramate and zonisamide. Unless a focal onset is clearly confirmed, a sodium-channel blocking AED should not be used in the initial treatment of these conditions.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.