ReviewThe Journal of craniofacial surgery2012
Palatal and oral manifestations of Muenke syndrome (FGFR3-related craniosynostosis).
Review in The Journal of craniofacial surgery, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 32 citations in OpenAlex.
- [A case report of Muenke syndrome with soft cleft palate and literature review].Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology · 2025Review
- [Application and development of orthognathic surgery in treatment of syndromic craniosynostosis].Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery · 2023Article
- New developments in the biology of fibroblast growth factors.WIREs mechanisms of disease · 2022Review
- Crouzon syndrome in a fraternal twin: A case report and review of the literature.World journal of clinical cases · 2022Article
- Genetic and Clinical Features of Heterotaxy in a Prenatal Cohort.Frontiers in genetics · 2022Article
- Fibroblast growth factor signalling in osteoarthritis and cartilage repair.Nature reviews. Rheumatology · 2020Review
- Article
- Genetic Causes of Craniosynostosis: An Update.Molecular syndromology · 2019Review
- Sagittal Craniosynostosis with Uncommon Anatomical Pathologies in a 56-Year-Old Male Cadaver.Case reports in pathology · 2019Article
- Development of Normal and Cleft Palate: A Central Role for Connective Tissue Growth Factor (CTGF)/CCN2.Journal of developmental biology · 2018Review
- Genetic Screening in Patients with Craniofacial Malformations.Journal of pediatric genetics · 2016Review
- Fuz mutant mice reveal shared mechanisms between ciliopathies and FGF-related syndromes.Developmental cell · 2013Article
- Phenotype profile of a genetic mouse model for Muenke syndrome.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2012Article
- Impact of genetics on the diagnosis and clinical management of syndromic craniosynostoses.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2012Review
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
Although Muenke syndrome is the most common syndromic form of craniosynostosis, the frequency of oral and palatal anomalies including high-arched palate, cleft lip with or without cleft palate has not been documented in a patient series of Muenke syndrome to date. Further, to our knowledge, cleft lip and palate has not been reported yet in a patient with Muenke syndrome (a previous patient with isolated cleft palate has been reported). This study sought to evaluate the frequency of palatal anomalies in patients with Muenke syndrome through both a retrospective investigation and literature review. A total of 21 patients who met criteria for this study were included in the retrospective review. Fifteen patients (71%) had a structural anomaly of the palate. Cleft lip and palate was present in 1 patient (5%). Other palatal findings included high-arched hard palate in 14 patients (67%). Individuals with Muenke syndrome have the lowest incidence of cleft palate among the most common craniosynostosis syndromes. However, high-arched palate in Muenke syndrome is common and may warrant clinical attention, as these individuals are more susceptible to recurrent chronic otitis media with effusion, dental malocclusion, and hearing loss.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.