Evidence map›Paper›PMID 22565613›Full record

ArticleAngewandte Chemie (International ed. in English)2012

Multi-timescale conformational dynamics of the SH3 domain of CD2-associated protein using NMR spectroscopy and accelerated molecular dynamics.

Loïc Salmon, Levi Pierce, Alexander Grimm, Jose-Luis Ortega Roldan, Luca Mollica, Malene Ringkjøbing Jensen, Nico van Nuland, Phineus R L Markwick, J Andrew McCammon, Martin Blackledge

Abstract read
In one paragraph

Article in Angewandte Chemie (International ed. in English), 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Contribution of protein conformational heterogeneity to NMR lineshapes at cryogenic temperatures.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Localization of Millisecond Dynamics: Dihedral Entropy from Accelerated MD.Journal of chemical theory and computation · 2016
    Article
  7. Review
  8. Article
  9. Article
  10. Review
  11. Article
  12. Review
  13. Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Loïc SalmonProtein Dynamics and Flexibility, Institut de Biologie Structurale Jean-Pierre Ebel, CNRS-CEA-UJF, UMR 5075, 41 rue Jules Horowitz, 38027 Grenoble Cedex, France.
Levi Pierce
Alexander Grimm
Jose-Luis Ortega Roldan
Luca Mollica
Malene Ringkjøbing Jensen
Nico van Nuland
Phineus R L Markwick
J Andrew McCammon
Martin Blackledge

Funding

National Biomedical Computation Resource - Competitive Revision SupplementP41GM103426 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI AMARO, ROMMIE E · 2012 to 2019
$14.0M
THEORY OF BIOMOLECULAR DIFFUSIONR01GM031749 · NIGMS · UNIVERSITY OF HOUSTON · PI HUBER, GARY ALEXANDER, MCCAMMON, JAMES ANDREW · 1985 to 2022
$7.8M
Howard Hughes Medical InstituteNIGMS NIH HHS P41 GM103426NIGMS NIH HHS R01 GM031749
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Molecular Dynamics SimulationAdaptor Proteins, Signal TransducingCytoskeletal ProteinsMagnetic Resonance SpectroscopyProteinssrc Homology DomainsAdaptor Proteins, Signal TransducingCD2-associated proteinCytoskeletal ProteinsProteins

Identifiers

PMID22565613
PMCPMC3541011

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.