Evidence map›Paper›PMID 22565475›Full record

ArticleMolecules (Basel, Switzerland)2012

Phaeophytin analogues from Ligularia knorringiana.

Hui Li, Lina Li, Qiusheng Zheng, Chiaki Kuroda, Qi Wang

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. New Cannabinoids and Chlorin-Type Metabolites from the Flowers ofPharmaceuticals (Basel, Switzerland) · 2025
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Hui LiKey Laboratory of Xin Jiang Phytomedicine Resources, School of Pharmacy, Shihezi University, Shihezi 832002, China.
Lina Li
Qiusheng Zheng
Chiaki Kuroda
Qi Wang

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A new phaeophytin, ligulariaphytin A, together with five known phaeophytins, were isolated from the aerial parts of Ligularia knorringiana. The structure of ligulariaphytin A was elucidated as 13¹-hydroxy-13¹,13²-peroxyphaeophorbide A ethyl ester, and the five known compounds were identified as 13²-hydroxyphaeophorbide A ethyl ester, 17³-ethoxyphaeophorbide A, phaeophytin B, phaeophytin A, and phaeophorbide B ethyl ester, respectively, based on spectroscopic analysis and by comparison of their spectral data with those reported previously in the literature. All compounds were evaluated for their in vitro cytotoxic activities against cultured Hela cell, and were found to show only very weak cytotoxicity.

Indexed as

Antineoplastic Agents, PhytogenicAsteraceaeCell SurvivalDrug Screening Assays, AntitumorHeLa CellsHumansMagnetic Resonance SpectroscopyMolecular StructurePheophytinsPlant Components, AerialPlant ExtractsAntineoplastic Agents, Phytogenicligulariaphytin APheophytinsPlant Extracts

Identifiers

PMID22565475
PMCPMC6268028

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.