ReviewPediatric cardiology2012
The growing epidemic of hypertension among children and adolescents: a challenging road ahead.
Review in Pediatric cardiology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it.
- EVIDENCE OF THE ASSOCIATION BETWEEN SLEEP DURATION AND BLOOD PRESSURE IN ADOLESCENTS: A SYSTEMATIC REVIEW.Revista paulista de pediatria : orgao oficial da Sociedade de Pediatria de Sao Paulo · 2021Pooled it
- Childhood Cardiovascular Health, Obesity, and Some Related Disorders: Insights into Chronic Inflammation and Oxidative Stress.International journal of molecular sciences · 2024Review
- Article
- The Impact of Secondary Hypertension in Pregnancy on Maternal and Fetal Outcomes: A 42-Month Observational Study from South India.Journal of obstetrics and gynaecology of India · 2022Article
- Surveillance of Hypertension Among Women of Reproductive Age: A Review of Existing Data Sources and Opportunities for Surveillance Before, During, and After Pregnancy.Journal of women's health (2002) · 2021Review
- Hypertension in adolescents and young adults referred to a tertiary hypertension clinic in Cape Town, South Africa.Medicine · 2020Article
- Impact of dyslipidemia on estimated glomerular filtration rate in apparently healthy children and adolescents: the CASPIAN-V study.World journal of pediatrics : WJP · 2019Article
- Impact of Body Mass Index on Postconcussion Symptoms in Teenagers Aged 13 to 18 Years.The Permanente journal · 2018Article
- The Association of Vitamin A and Vitamin D with Hypertension in Children: A Case-Control Study.International journal of hypertension · 2018Article
- Renin-angiotensin system gene polymorphisms and high blood pressure in Lithuanian children and adolescents.BMC medical genetics · 2017Article
- Hypertension in pediatric patients with chronic kidney disease: management challenges.International journal of nephrology and renovascular disease · 2017Review
- Nanoformulated copper/zinc superoxide dismutase attenuates vascular cell activation and aortic inflammation in obesity.Biochemical and biophysical research communications · 2016Article
- Hypertension in Young People: Epidemiology, Diagnostic Assessment and Therapeutic Approach.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2015Review
- Sleep characteristics, body mass index, and risk for hypertension in young adolescents.Journal of youth and adolescence · 2015Article
- Childhood obesity, arterial stiffness, and prevalence and treatment of hypertension.Current treatment options in cardiovascular medicine · 2014Article
- Diagnosis and screening for obesity-related conditions among children and teens receiving Medicaid--Maryland, 2005-2010.MMWR. Morbidity and mortality weekly report · 2014Article
- Prehypertension: a warning sign of future cardiovascular risk.International journal of preventive medicine · 2014Review
- Resistant hypertension: current status, future challenges.International journal of preventive medicine · 2014Review
- Management of hypertension in children with cardiovascular disease and heart failure.International journal of preventive medicine · 2014Review
- Childhood hypertension: a problem of epidemic proportion.International journal of preventive medicine · 2014Article
Corrections and comments
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Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Currently, it is clear that primary hypertension begins in childhood and that it contributes to the early development of chronic kidney disease (CKD). Hypertension also increases the risk of cardiovascular morbidity and mortality, and that risk rises as blood pressure levels escalate. As among adult patients, overweight and obesity rates are on the rise among children and adolescents with primary hypertension and can develop target organ damage including left ventricular hypertrophy. An elevated level of C-reactive protein (CRP) and microalbuminuria are early manifestations of cardiovascular disease and CKD in hypertensive patients. Lifestyle interventions are recommended for all children with hypertension. Pharmacologic therapy should be added for symptomatic children, those with stage 2 hypertension, and children with prehypertension and stage 1 hypertension who exhibit an insufficient response to lifestyle modifications. Although the recommendations for choice of drugs generally are similar for children and adults, dosages for children should be lower, based on weight, and adjusted very carefully. Medications that are effective and safe for children and adolescents include thiazide diuretics, angiotensin-converting enzyme inhibitors, angiotensin receptor blockers, beta-blockers, and calcium channel-blockers. Hypertension is not being detected early enough for initiation of a treatment regimen to reduce death and disability. Initiatives should be undertaken to make health care providers and the general population more aware of the seriousness of hypertension in children and adolescents. This review focuses on the principles underlying the importance of a team approach for hypertension control, especially one that incorporates increased data sharing using enhanced health information technology for early detection and intervention.
Indexed as
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.