Hepatocyte-like cells differentiated from human induced pluripotent stem cells (iHLCs) are permissive to hepatitis C virus (HCV) infection: HCV study gets personal.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

1. Guidelines for the use of cell lines in biomedical research.British journal of cancer · 2014
   Guideline
2. Development of Hepatocyte-like Cell Derived from Human Induced Pluripotent Stem cell as a Host for Clinically Isolated Hepatitis C Virus.Current protocols in stem cell biology · 2017
   Article
3. A robust model of natural hepatitis C infection using hepatocyte-like cells derived from human induced pluripotent stem cells as a long-term host.Virology journal · 2016
   Article
4. Malaria modeling: In vitro stem cells vs in vivo models.World journal of stem cells · 2016
   Review
5. Mechanisms of HCV-induced liver cancer: what did we learn from in vitro and animal studies?Cancer letters · 2014
   Review
6. Clinical therapy using iPSCs: hopes and challenges.Genomics, proteomics & bioinformatics · 2013
   Review
7. Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in investigating mechanisms of hepatotoxicity, cell signaling and ADME.Archives of toxicology · 2013
   Review
8. In vitro systems for the study of hepatitis C virus infection.International journal of hepatology · 2012
   Article

Corrections and comments

• Comment on
  Modeling hepatitis C virus infection using human induced pluripotent stem cells.2012

Authors and funding

3 authors.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.