SynthesisAlcoholism, clinical and experimental research2012
The relationship between alcohol consumption and fatal motor vehicle injury: high risk at low alcohol levels.
Synthesis in Alcoholism, clinical and experimental research, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
45 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- A Systematic Review of the Risks of Motor Vehicle Crashes Associated with Psychiatric Disorders.Canadian journal of psychiatry. Revue canadienne de psychiatrie · 2023Pooled it
- Alcohol consumption for simulated driving performance: A systematic review.Chinese journal of traumatology = Zhonghua chuang shang za zhi · 2017Pooled it
- The relationship between different dimensions of alcohol use and the burden of disease-an update.Addiction (Abingdon, England) · 2017Pooled it
- Discrepancies between self-reported alcohol use and breathalyzer results and factors associated with blood alcohol concentration positivity among road traffic injury patients in Cameroon.Addiction (Abingdon, England) · 2026Article
- Role of socioeconomic status in modifying the relationship between alcohol use and injury events: evidence from the UK Biobank.Journal of epidemiology and community health · 2026Article
- A randomised, double-blind, placebo-controlled trial examining the dose-dependent effects of acute alcohol intoxication on neurocognitive performance.Psychopharmacology · 2026Article
- Per Se Driving Under the Influence of Cannabis Statutes and Blood Delta-9-Tetrahydrocannabinol Concentrations following Short-Term Cannabis Abstinence.Clinical chemistry · 2025Article
- The eyes have it: Alcohol-induced eye movement impairment and perceived impairment in older adults with and without alcohol use disorder.Alcohol, clinical & experimental research · 2025Article
- What is the lifetime cost of alcohol consumption? an estimation of economic burden in Thailand.PloS one · 2025Article
- The Association of Alcohol Outlet Density With Alcohol Intake: The Multiethnic Cohort.Journal of studies on alcohol and drugs · 2024Article
- Substance use and type of Road Traffic Injury in Mexico City.Journal of prevention (2022) · 2024Article
- Individual characteristics associated with road traffic collisions and healthcare seeking in low- and middle-income countries and territories.PLOS global public health · 2024Article
- Associations between alcohol intake and hospital contacts due to alcohol and unintentional injuries in 71,025 Danish adolescents - a prospective cohort study.EClinicalMedicine · 2023Article
- The absence of data on driving under the influence of alcohol in road traffic studies: a scoping review of non-randomized studies with vote counting based on the direction of effects of alcohol policies.Substance abuse treatment, prevention, and policy · 2023Article
- Risk of Motor Vehicle Collisions and Culpability among Older Drivers Using Cannabis: A Meta-Analysis.Brain sciences · 2023Review
- Assessing the health impacts of transnational corporations: a case study of Carlton and United Breweries in Australia.Globalization and health · 2022Article
- Article
- A Framing Analysis of Consultation Submissions on the WHO Global Strategy to Reduce the Harmful Use of Alcohol: Values and Interests.International journal of health policy and management · 2022Article
- Alcohol and health. Is regular drinking of small doses of alcohol really good for your health?Archives of medical sciences. Atherosclerotic diseases · 2022Article
- Rideshare Trips and Alcohol-Involved Motor Vehicle Crashes in Chicago.Journal of studies on alcohol and drugs · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
backgroundAlcohol consumption causes motor vehicle accident (MVA) injury in a dose-response fashion. However, the relationship between how this risk is different with respect to fatal and nonfatal outcomes is not clear. A meta-analysis has already been completed for alcohol consumption and nonfatal MVA injury, but none exists for fatal injury. Thus, an analysis of the acute dose-response relationship between alcohol and motor vehicle injury death is warranted to generate single occasion- and dose-specific relative risks for the first time.
methodsA systematic literature review and inverse-variance weighted, random effects meta-analysis were conducted to fill this gap. Fractional polynomial regression was used to model the dose-response relationship. Usual tests of heterogeneity and publication bias were run.
resultsFive studies meeting the inclusion criteria of this analysis were selected. At all levels of blood alcohol concentration (BAC), the odds ratio (OR) of fatal motor vehicle injury was significant. Overall, the 5 combined studies yielded an OR of fatal injury of 1.74 (95% CI: 1.43-2.14) for every 0.02% increase in BAC. At 0.08, the legal limit in most countries, the OR was 13.0 (95% CI: 11.1-15.2).
conclusionsThis study is able to definitively show and quantify, for the first time, the significantly increased OR for fatal motor vehicle injury. This analysis showed some evidence of both study heterogeneity and publication bias, likely due to the increased variation we could expect from a small study number. The alcohol-caused fatal motor vehicle injury literature is sparse with respect to dose-response information. More studies investigating this relationship and other injury types are recommended in this area to be able to calculate stable estimates of risk overall and by injury type specifically.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.