Trial reportJournal of consulting and clinical psychology2012
Randomized clinical trial of cognitive behavioral therapy (CBT) versus acceptance and commitment therapy (ACT) for mixed anxiety disorders.
Trial report in Journal of consulting and clinical psychology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 98 papers, 14 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
98 citing papers in PubMed, 14 syntheses or guidelines pooled it, 427 citations in OpenAlex.
- Examining the relationship between pre-treatment anhedonia and treatment outcomes in individuals with anxiety or depression: A systematic review.Journal of affective disorders · 2026Pooled it
- Mapping cognitive-behavioral approach in psychedelic-assisted treatment: a systematic review across phases with classic and non-classic psychedelics.European archives of psychiatry and clinical neuroscience · 2026Pooled it
- The Efficacy of Acceptance and Commitment Therapy for Reducing Anxiety in Parents of Children With Special Needs: A Meta-Analysis.Research on child and adolescent psychopathology · 2026Pooled it
- Acceptance and commitment therapy among caregivers of people with cancer: a systematic review and meta-analysis.Scientific reports · 2025Pooled it
- Psychosocial interventions for anxiety disorders in adults: evidence mapping and guideline appraisal.Frontiers in psychiatry · 2025Pooled it
- Effect of acceptance and commitment therapy for adolescent depression: a meta-analysis.Frontiers in psychiatry · 2025Pooled it
- Cognitive behavioural therapy and third-wave approaches for anxiety and related disorders in older people.The Cochrane database of systematic reviews · 2024Pooled it
- Psychotherapies for Generalized Anxiety Disorder in Adults: A Systematic Review and Network Meta-Analysis of Randomized Clinical Trials.JAMA psychiatry · 2024Pooled it
- A systematic review and meta-analysis of acceptance- and mindfulness-based interventions for DSM-5 anxiety disorders.Scientific reports · 2021Pooled it
- Acceptance and commitment therapy in adult cancer survivors: a systematic review and conceptual model.Journal of cancer survivorship : research and practice · 2021Pooled it
- A systematic review and meta-analysis of mindfulness- and acceptance-based interventions for affect intolerance/sensitivity.Behaviour research and therapy · 2020Pooled it
- Pooled it
- Psychological therapies for panic disorder with or without agoraphobia in adults: a network meta-analysis.The Cochrane database of systematic reviews · 2016Pooled it
- Effect of cognitive-behavioral therapy for anxiety disorders on quality of life: a meta-analysis.Journal of consulting and clinical psychology · 2014Pooled it
- Internet-Based Acceptance and Commitment Therapy With Interoceptive Exposure for Panic Disorder: A Randomized Controlled Trial and Working Alliance Analysis.Scandinavian journal of psychology · 2026Trial
- Effect of Acceptance and Commitment Therapy on Motivation and Adherence to Immunosuppressive Medication in Liver Transplant Recipients: A Randomized Controlled Trial.Brain and behavior · 2025Trial
- A digital intervention for cognitive deficits following COVID-19: a randomized clinical trial.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2024Trial
- Blended Acceptance and Commitment Therapy Versus Face-to-face Cognitive Behavioral Therapy for Older Adults With Anxiety Symptoms in Primary Care: Pragmatic Single-blind Cluster Randomized Trial.Journal of medical Internet research · 2021Trial
- Isolating the Effects of Mindfulness Training Across Anxiety Disorder Diagnoses in the Unified Protocol.Behavior therapy · 2020Trial
- Trajectories of change in well-being during cognitive behavioral therapies for anxiety disorders: Quantifying the impact and covariation with improvements in anxiety.Psychotherapy (Chicago, Ill.) · 2020Trial
38 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 4 institutions in 1 country.
Funding
Abstract
objectiveRandomized comparisons of acceptance-based treatments with traditional cognitive behavioral therapy (CBT) for anxiety disorders are lacking. To address this gap, we compared acceptance and commitment therapy (ACT) to CBT for heterogeneous anxiety disorders.
methodOne hundred twenty-eight individuals (52% female, mean age = 38, 33% minority) with 1 or more DSM-IV anxiety disorders began treatment following randomization to CBT or ACT; both treatments included behavioral exposure. Assessments at pre-treatment, post-treatment, and 6- and 12-month follow-up measured anxiety-specific (principal disorder Clinical Severity Ratings [CSRs], Anxiety Sensitivity Index, Penn State Worry Questionnaire, Fear Questionnaire avoidance) and non-anxiety-specific (Quality of Life Index [QOLI], Acceptance and Action Questionnaire-16 [AAQ]) outcomes. Treatment adherence, therapist competency ratings, treatment credibility, and co-occurring mood and anxiety disorders were investigated.
resultsCBT and ACT improved similarly across all outcomes from pre- to post-treatment. During follow-up, ACT showed steeper linear CSR improvements than CBT (p < .05, d = 1.26), and at 12-month follow-up, ACT showed lower CSRs than CBT among completers (p < .05, d = 1.10). At 12-month follow-up, ACT reported higher AAQ than CBT (p = .08, d = 0.42; completers: p < .05, d = 0.56), whereas CBT reported higher QOLI than ACT (p < .05, d = 0.42). Attrition and comorbidity improvements were similar; ACT used more non-study psychotherapy at 6-month follow-up. Therapist adherence and competency were good; treatment credibility was higher in CBT.
conclusionsOverall improvement was similar between ACT and CBT, indicating that ACT is a highly viable treatment for anxiety disorders.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.