Evidence map›Paper›PMID 22563295›Full record

ArticleInternational journal of mass spectrometry2012

A Review of Tandem Mass Spectrometry Characterization of Adenosine Diphosphate-Ribosylated Peptides.

Shawna M Hengel, David R Goodlett

Abstract read
In one paragraph

Article in International journal of mass spectrometry, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Are PARPs promiscuous?Bioscience reports · 2022
    Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Shawna M HengelDepartment of Medicinal Chemistry, University of Washington, Box 357610 Seattle WA 98195-7610 U.S.A.
David R Goodlett

Funding

Variation in Human Innate ImmunityU54AI057141 · NIAID · UNIVERSITY OF WASHINGTON · PI COOKSON, BRAD T · 2003 to 2013
$102.3M
Pharmacological Sciences SupplementT32GM007750 · NIGMS · UNIVERSITY OF WASHINGTON · PI ATKINS, WILLIAM M · 1985 to 2023
$12.6M
SpyA, a novel S. pyogenes ADP-ribosyltransferaseR01AI064515 · NIAID · UNIVERSITY OF WASHINGTON · PI MOSELEY, STEPHEN L. · 2006 to 2010
$1.7M
Fourier transform-ion cyclotron-resonance mass specS10RR017262 · NCRR · INSTITUTE FOR SYSTEMS BIOLOGY · PI GOODLETT, DAVID ROBINSON · 2003 to 2003
$782k
MULTI-TIERED PROTEOMIC COMPUTE CLUSTER: PARKINSON'S DISEASES10RR023044 · NCRR · UNIVERSITY OF WASHINGTON · PI GOODLETT, DAVID ROBINSON · 2006 to 2006
$500k
NCRR NIH HHS S10 RR017262NCRR NIH HHS S10 RR023044NIAID NIH HHS R01 AI064515NIAID NIH HHS U54 AI057141NIGMS NIH HHS T32 GM007750
6 · The paper itself

Abstract

The use of tandem mass spectrometry to identify and characterize sites of protein adenosine diphosphate (ADP) ribosylation will be reviewed. Specifically, we will focus on data acquisition schemes and fragmentation techniques that provide peptide sequence and modification site information. Also discussed are uses of synthetic standards to aid characterization, and an enzymatic method that converts ADP-ribosylated peptides into ribosyl mono phosphorylated peptides making identification amenable to traditional phosphopeptide characterization methods. Finally the potential uses of these techniques to characterize poly ADP-ribosylation sites, and inherent challenges, are addressed.

Identifiers

PMID22563295
PMCPMC3341133

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.