ArticleHernia : the journal of hernias and abdominal wall surgery2012
Modified classification of surgical meshes for hernia repair based on the analyses of 1,000 explanted meshes.
Article in Hernia : the journal of hernias and abdominal wall surgery, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 69 papers, 4 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
69 citing papers in PubMed, 4 syntheses or guidelines pooled it, 188 citations in OpenAlex.
- Meta-analysis of postoperative pain using non-sutured or sutured single-layer open mesh repair for inguinal hernia.BJS open · 2019Pooled it
- International guidelines for groin hernia management.Hernia : the journal of hernias and abdominal wall surgery · 2018Guideline
- Laparoscopic ventral/incisional hernia repair: updated Consensus Development Conference based guidelines [corrected].Surgical endoscopy · 2015Guideline
- What do we know about titanized polypropylene meshes? An evidence-based review of the literature.Hernia : the journal of hernias and abdominal wall surgery · 2014Pooled it
- Onlay mesh versus suture repair for smaller umbilical hernias in adults-early results from SUMMER trial: randomized clinical trial.BJS open · 2024Trial
- Trial
- Titanium-coated mesh versus standard polypropylene mesh in laparoscopic inguinal hernia repair: a prospective, randomized, controlled clinical trial.Hernia : the journal of hernias and abdominal wall surgery · 2019Trial
- Long-term retromuscular and intraperitoneal mesh size changes within a randomized controlled trial on incisional hernia repair, including a review of the literature.Hernia : the journal of hernias and abdominal wall surgery · 2017Trial
- Macroscopic, radiologic, and microscopic analysis of explanted abdominal wall prosthesis.Hernia : the journal of hernias and abdominal wall surgery · 2026Article
- Rectus diastasis is not a single entity: phenotype-specific controversies in surgical management.Hernia : the journal of hernias and abdominal wall surgery · 2026Review
- Mapping the Prosthetic-Host Interactome: From Systemic Inflammation to Biological Integration in Mesh-Enhanced Therapies METs-A Scoping Review.International journal of molecular sciences · 2026Article
- Extended validation of the mesh integration (MINT) index: a 1-year porcine study.Surgical endoscopy · 2026Article
- Development of a Tissue-Based Extracellular Matrix Vulnerability Score (ECM-V) for Women Undergoing Primary Pelvic Organ Prolapse Surgery.Biomedicines · 2026Article
- Intraperitoneal Polypropylene Mesh in Clean, Potentially Septic, and Controlled Contamination Fields: An Experimental Rat Study.Medicina (Kaunas, Lithuania) · 2026Article
- Nano-Structural Characterization of Human Aponeurotic Tissue by Atomic Force Microscopy.Biomedicines · 2026Article
- Validating the mesh integration (MINT) index: a 3-month porcine study.Surgical endoscopy · 2026Article
- Article
- Assessing the Impact of Morphological Parameters on the Mechanical Behavior of Synthetic Meshes. A Multivariate Regression Approach.International journal for numerical methods in biomedical engineering · 2025Article
- To infinity and beyond: the promise of data-driven 3D printing of hernia mesh - a primer for surgeons.Hernia : the journal of hernias and abdominal wall surgery · 2025Review
- Lightweight versus heavyweight synthetic mesh for inguinal hernia repair.The Cochrane database of systematic reviews · 2025Article
9 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIt is an undisputable fact that meshes have become standard for repair of abdominal wall hernias. Whereas in the late eighties there were only a couple of different devices available, today we have to choose among some hundreds, with lots of minor and major variations in polymer and structure. As most of the minor variations may not lead to significant change in clinical outcome and may be regarded as less relevant, we should focus on major differences. Eventually, this is used to structure the world of mesh by forming groups of textile devices with distinct biological response. Many experimental and some clinical studies have underlined the outstanding importance of porosity, which fortunately, in contrast to other biomechanical quanlities, is widely unaffected by the anisotropy of meshes.
methodsIn accordance with the major manufacturers of meshes, a classification of meshes was derived from a huge pool of textile data based briefly on the following: (1) large pores, (2) small pores, (3) additional features, (4) no pores, (5) 3D structure and (6) biological origin. At 1,000 explanted meshes the value of this classification was evaluated by group-specific assessment of inflammatory and connective tissue reaction.
resultsApplication of this classification to common products has proved feasable, and each of the six different classes includes devices that in clinical trials failed to show relevant differences in patients' outcome when comparing products within the same group. Furthermore, histological analysis confirmed significant differences in tissue reactions between but not within the different classes.
conclusionsClassifying implants according to a similar response enables grouping patients into comparable cohorts despite implantation of different devices. Furthermore, it enables the examination of the impact of mesh classes for the various indications even from heterogenous data of registries. Finally and not the least, any grouping supports the surgeon to select the best device to meet the individual need and to tailor patients therapy.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.