ArticleDer Internist2012
[Therapeutic targets in arterial hypertension and diabetes mellitus. Can medical prevention be harmful?].
Article in Der Internist, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed, 4 citations in OpenAlex.
No citing paper in PubMed yet.
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Arterial hypertension contributes considerably to the increased cardiorenal risk of patients with diabetes mellitus type 2. Therefore guideline-writing authorities recommend starting antihypertensive treatment generously, with the aim of reducing blood pressure to levels to < 130/80 mmHg. Nevertheless, results of several recent studies have challenged the currently prevailing paradigm "the lower the better" in hypertension management. A similar paradigm also seems to hold true for the management of blood glucose in these patients. Detailed analyses have shown an increased risk of coronary events by targeting both lower blood pressure and blood glucose levels, especially in those with established cardiovascular disease and especially coronary artery disease--thus, the concept of "the lower the better" should be reconsidered in this group of patients.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.