Evidence map›Paper›PMID 22562082›Full record

Trial reportBone marrow transplantation2012

Comparison of early quality of life outcomes in autologous and allogeneic transplant patients.

C M Garcia, P B Mumby, S Thilges, P J Stiff

Abstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Bone marrow transplantation, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Trial
  2. Observational
  3. Observational
  4. Exercise in allogeneic bone marrow transplantation: a qualitative representation of the patient perspective.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2022
    Article
  5. Review
  6. Functional capacity, pulmonary function, and quality of life in hematopoietic stem cell transplantation survivors.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2021
    Article
  7. Observational
  8. Everyday life following hematopoietic stem cell transplantation: decline in physical symptoms within the first month and change-related predictors.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2018
    Article
  9. Article
  10. Myeloma in Elderly Patients: When Less Is More and More Is More.American Society of Clinical Oncology educational book. American Society of Clinical Oncology. Annual Meeting · 2017
    Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

C M GarciaCollege of Psychology, Illinois Institute of Technology, Chicago, IL, USA.
P B Mumby
S Thilges
P J Stiff

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The Functional Assessment of Cancer Therapy-Bone Marrow Transplant measures quality of life (QOL) in SCT patients. Prior reports found mixed results regarding QOL differences among autologous and allogeneic SCT patients. In addition, there is a paucity of literature examining differences in QOL patterns over time between autologous and allogeneic patients. The present study examines differences in QOL between patients free of clinical depression undergoing autologous (n = 41) and allogeneic (n = 64) SCT during early stages of treatment. Despite clinical differences, autologous and allogeneic patients demonstrated similar changes in QOL. The exception was the Functional subscale which indicated worse QOL for allogeneic patients at discharge (F test = 4.61, df = 1, P < 0.05); allogeneic patients (Mean = 13.06, s.d. = 5.36) indicated they were less able to function at work and were less accepting of their illness than autologous patients (Mean = 16.02, s.d. = 6.73). There was a significant main effect for time on nearly all QOL subscales (P < 0.05) demonstrating decline during treatment and return to baseline by discharge; only the Social Well-Being scale did not significantly change over time. These results help to understand patients' response to SCT in the earliest stages and ultimately help identify patients at risk who could benefit from therapeutic interventions.

Indexed as

Antidepressive AgentsDepressionDouble-Blind MethodFemaleHumansMaleMiddle AgedNeoplasmsQuality of LifeSertralineStem Cell TransplantationTransplantation, AutologousTransplantation, HomologousTreatment OutcomeAntidepressive AgentsSertraline

Identifiers

PMID22562082

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.