Evidence map›Paper›PMID 22561817›Full record

ArticleNature medicine2012

Germs gone wild.

Namiko Hoshi, Ruslan Medzhitov

Abstract readComment
PubMed Full text at PMC Publisher
In one paragraph

Article in Nature medicine, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Namiko HoshiHoward Hughes Medical Institute and Yale University Medical School, New Haven, Connecticut, USA.
Ruslan Medzhitov

Funding

TLRs in Host Commensal InteractionsR01DK071754 · NIDDK · YALE UNIVERSITY · PI MEDZHITOV, RUSLAN · 2007 to 2014
$2.8M
NIDDK NIH HHS R01 DK071754
6 · The paper itself

Abstract

The normally harmless behavior of bacteria in the intestinal tract is maintained by community structure and the integrity of host defenses. When either or both of these are compromised, a few disgruntled outcasts can cause a riot, taking down the whole neighborhood (pages 799-806).

Indexed as

AnimalsAnti-Bacterial AgentsApoptosis Regulatory ProteinsCalcium-Binding ProteinsEscherichia coliInflammasomesIntestinesMetagenomeNeuronal Apoptosis-Inhibitory ProteinAnti-Bacterial AgentsApoptosis Regulatory ProteinsCalcium-Binding ProteinsInflammasomesIpaf protein, mouseNaip5 protein, mouseNeuronal Apoptosis-Inhibitory Protein

Identifiers

PMID22561817
PMCPMC3698559

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.