ArticleNature medicine2012
Activation of BK channels may not be required for bitter tastant-induced bronchodilation.
Article in Nature medicine, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed.
- Molecular mechanism of bitter taste receptor agonist-mediated relaxation of airway smooth muscle.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2024Article
- Article
- Tas2R activation relaxes airway smooth muscle by release of GαProceedings of the National Academy of Sciences of the United States of America · 2022Article
- Bitter Taste Receptors in the Airway Cells Functions.Handbook of experimental pharmacology · 2022Article
- Mutation analysis and prenatal diagnosis of a family with congenital contractural arachnodactyly.Molecular genetics & genomic medicine · 2021Article
- Clinical Role of Extraoral Bitter Taste Receptors.International journal of molecular sciences · 2020Review
- Therapeutic potential and challenges of bitter taste receptors on lung cells.Current opinion in pharmacology · 2020Review
- Bitter Taste Receptors: an Answer to Comprehensive Asthma Control?Current allergy and asthma reports · 2019Review
- Toward the Identification of Extra-Oral TAS2R Agonists as Drug Agents for Muscle Relaxation Therapies via Bioinformatics-Aided Screening of Bitter Compounds in Traditional Chinese Medicine.Frontiers in physiology · 2019Article
- Bitter Taste Receptors for Asthma Therapeutics.Frontiers in physiology · 2019Article
- Chloroquine is a potent pulmonary vasodilator that attenuates hypoxia-induced pulmonary hypertension.British journal of pharmacology · 2017Article
- Extraoral bitter taste receptors in health and disease.The Journal of general physiology · 2017Review
- Activation of bitter taste receptors (tas2rs) relaxes detrusor smooth muscle and suppresses overactive bladder symptoms.Oncotarget · 2016Article
- Evaluation of Mucociliary Clearance by Three Dimension Micro-CT-SPECT in Guinea Pig: Role of Bitter Taste Agonists.PloS one · 2016Article
- Article
- Rosiglitazone is a superior bronchodilator compared to chloroquine and β-adrenoceptor agonists in mouse lung slices.Respiratory research · 2014Article
- Bitter tasting compounds dilate airways by inhibiting airway smooth muscle calcium oscillations and calcium sensitivity.British journal of pharmacology · 2014Article
- Bitter taste receptors in the wrong place: novel airway smooth muscle targets for treating asthma.Transactions of the American Clinical and Climatological Association · 2014Article
- Non-selective cation channels mediate chloroquine-induced relaxation in precontracted mouse airway smooth muscle.PloS one · 2014Article
- The expression and relaxant effect of bitter taste receptors in human bronchi.Respiratory research · 2013Article
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Authors and funding
6 authors.
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Abstract
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.