ReviewTrends in endocrinology and metabolism: TEM2012
The endocrine effects of nicotine and cigarette smoke.
Review in Trends in endocrinology and metabolism: TEM, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 96 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
96 citing papers in PubMed, 3 syntheses or guidelines pooled it, 223 citations in OpenAlex.
- Association between electronic cigarette use and prediabetes, diabetes, and insulin resistance: a systematic review and meta-analysis.Internal and emergency medicine · 2026Pooled it
- Sexually dimorphic response to tobacco exposure in COPD: a systematic review and meta-analysis.BMC pulmonary medicine · 2026Pooled it
- The Effects of E-Cigarette Vapor Components on the Morphology and Function of the Male and Female Reproductive Systems: A Systematic Review.International journal of environmental research and public health · 2020Pooled it
- Contribution of Consumer Products to Emerging Chemical Exposures in a Preconception Cohort Study.Environmental science & technology · 2026Article
- Serum cotinine-assessed tobacco exposure, cadmium co-exposure, and childhood obesity: a cross-sectional study.Environmental health : a global access science source · 2026Article
- Exposure of male mice to nicotine leads to metabolic dysfunction in their male and female offspring.Journal of the Endocrine Society · 2026Article
- Extracellular Vesicles and Endocrine Disruption: How Environmental Pollutants Modulate the Loading and Release of Extracellular Vesicles for Cancer Promotion and Progression.International journal of molecular sciences · 2026Review
- Prevalence of smoking and factors associated with smoking cessation among diabetic patients in Chongqing, China: A cross-sectional study.Tobacco induced diseases · 2026Article
- Heated Tobacco Products: Emerging Health Outcomes and Insights into Oxidative Stress and Pro-Inflammatory-Driving Mechanisms.Antioxidants (Basel, Switzerland) · 2025Review
- Pervasive environmental contaminant acrolein compromises myocardial geometry and function through the induction of cuproptosis.Acta biochimica et biophysica Sinica · 2025Article
- E-cigarette exposure and CDP choline modulate withdrawal- induced anxiety and hormonal levels in rats.Scientific reports · 2025Article
- METS-IR and SII as mediators in the association between smoking and depressive symptoms: insights from NHANES (2005-2018).BMC psychiatry · 2025Article
- Observational
- Review
- Body Composition and Metabolic Profiles in Young Adults: A Cross-Sectional Comparison of People Who Use E-Cigarettes, People Who Smoke Cigarettes, and People Who Have Never Used Nicotine Products.Journal of clinical medicine · 2025Article
- Snus and Cardiometabolic Health Markers Among Swedish Young Adults.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2025Article
- Smoking and endometriosis: A narrative review.Tobacco induced diseases · 2025Review
- Cholesterol Accumulation Enhances Cigarette Smoke-Induced Airway Epithelial Inflammation.International journal of chronic obstructive pulmonary disease · 2025Article
- Exposure to Environmental Chemicals and Infertility Among US Reproductive-Aged Women.International journal of environmental research and public health · 2024Article
- The Concentration of Follistatin and Activin A in Serum and Selected Biochemical Parameters in Women with Polycystic Ovary Syndrome: Stratification by Tobacco Smoke Exposure, Insulin Resistance, and Overweight/Obesity.Journal of clinical medicine · 2024Article
36 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
With a current prevalence of approximately 20%, smoking continues to impact negatively upon health. Tobacco or nicotine use influences the endocrine system, with important clinical implications. In this review we critically evaluate the literature concerning the impact of nicotine as well as tobacco use on several parameters of the endocrine system and on glucose and lipid homeostasis. Emphasis is on the effect of smoking on diabetes mellitus and obesity and the consequences of smoking cessation on these disorders. Understanding the effects of nicotine and cigarettes on the endocrine system and how these changes contribute to the pathogenesis of various endocrine diseases will allow for targeted therapies and more effective approaches for smoking cessation.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.