ArticleHearing research2012
Two-channel recording of auditory-evoked potentials to detect age-related deficits in temporal processing.
Article in Hearing research, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.
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Who cites it
38 citing papers in PubMed.
- Altered Auditory Maturation in Fragile X Syndrome and Its Involvement in Audiogenic Seizure Susceptibility.Autism research : official journal of the International Society for Autism Research · 2026Article
- Article
- The slowest timescales of neural synchronization reveal the strongest influence of auditory distraction.Frontiers in human neuroscience · 2025Article
- DX243 counteracts both acoustic trauma-induced reduction in cortical brain oscillations and cochlear synaptopathy.Frontiers in pharmacology · 2025Article
- Sensory representations and pupil-indexed listening effort provide complementary contributions to multi-talker speech intelligibility.Scientific reports · 2024Article
- Rapid and objective assessment of auditory temporal processing using dynamic amplitude-modulated stimuli.Communications biology · 2024Article
- Practical Bayesian Inference in Neuroscience: Or How I Learned to Stop Worrying and Embrace the Distribution.eNeuro · 2024Article
- Practical Bayesian Inference in Neuroscience: Or How I Learned To Stop Worrying and Embrace the Distribution.bioRxiv : the preprint server for biology · 2024Article
- Characterization and closed-loop control of infrared thalamocortical stimulation produces spatially constrained single-unit responses.PNAS nexus · 2024Article
- Neural hyperactivity and altered envelope encoding in the central auditory system: Changes with advanced age and hearing loss.Hearing research · 2024Review
- Rapid and objective assessment of auditory temporal processing using dynamic amplitude-modulated stimuli.bioRxiv : the preprint server for biology · 2024Article
- Spatially specific, closed-loop infrared thalamocortical deep brain stimulation.bioRxiv : the preprint server for biology · 2023Article
- Cortical-brainstem interplay during speech perception in older adults with and without hearing loss.Frontiers in neuroscience · 2023Article
- Loss of central mineralocorticoid or glucocorticoid receptors impacts auditory nerve processing in the cochlea.iScience · 2022Article
- Methodological considerations when measuring and analyzing auditory steady-state responses with multi-channel EEG.Current research in neurobiology · 2022Article
- Comparison of Auditory Steady-State Responses With Conventional Audiometry in Older Adults.Frontiers in neurology · 2022Article
- Longitudinal auditory pathophysiology following mild blast-induced trauma.Journal of neurophysiology · 2021Article
- Envelope following responses predict speech-in-noise performance in normal-hearing listeners.Journal of neurophysiology · 2021Article
- Neural Generators Underlying Temporal Envelope Processing Show Altered Responses and Hemispheric Asymmetry Across Age.Frontiers in aging neuroscience · 2020Article
- Afferent-efferent connectivity between auditory brainstem and cortex accounts for poorer speech-in-noise comprehension in older adults.Hearing research · 2019Article
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
Auditory brainstem responses (ABRs), and envelope and frequency following responses (EFRs and FFRs) are widely used to study aberrant auditory processing in conditions such as aging. We have previously reported age-related deficits in auditory processing for rapid amplitude modulation (AM) frequencies using EFRs recorded from a single channel. However, sensitive testing of EFRs along a wide range of modulation frequencies is required to gain a more complete understanding of the auditory processing deficits. In this study, ABRs and EFRs were recorded simultaneously from two electrode configurations in young and old Fischer-344 rats, a common auditory aging model. Analysis shows that the two channels respond most sensitively to complementary AM frequencies. Channel 1, recorded from Fz to mastoid, responds better to faster AM frequencies in the 100-700 Hz range of frequencies, while Channel 2, recorded from the inter-aural line to the mastoid, responds better to slower AM frequencies in the 16-100 Hz range. Simultaneous recording of Channels 1 and 2 using AM stimuli with varying sound levels and modulation depths show that age-related deficits in temporal processing are not present at slower AM frequencies but only at more rapid ones, which would not have been apparent recording from either channel alone. Comparison of EFRs between un-anesthetized and isoflurane-anesthetized recordings in young animals, as well as comparison with previously published ABR waveforms, suggests that the generators of Channel 1 may emphasize more caudal brainstem structures while those of Channel 2 may emphasize more rostral auditory nuclei including the inferior colliculus and the forebrain, with the boundary of separation potentially along the cochlear nucleus/superior olivary complex. Simultaneous two-channel recording of EFRs help to give a more complete understanding of the properties of auditory temporal processing over a wide range of modulation frequencies which is useful in understanding neural representations of sound stimuli in normal, developmental or pathological conditions.
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