ArticleThe Journal of thoracic and cardiovascular surgery2013
Simulating hemodynamics of the Fontan Y-graft based on patient-specific in vivo connections.
Article in The Journal of thoracic and cardiovascular surgery, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- Comparing pre- and post-operative Fontan hemodynamic simulations: implications for the reliability of surgical planning.Annals of biomedical engineering · 2012Trial
- Y-shaped pulmonary artery in modified Fontan surgery: a multimodality imaging case.Quantitative imaging in medicine and surgery · 2026Article
- The outcome of extracardiac lateral tunnel total cavopulmonary connection with growing conduit using expanded polytetrafluoroethylene graft.General thoracic and cardiovascular surgery · 2026Article
- Multiphysiologic State Computational Fluid Dynamics Modeling for Planning Fontan With Interrupted Inferior Vena Cava.JACC. Advances · 2024Article
- Predicting Hemodynamic Performance of Fontan Operation for Glenn Physiology using Computational Fluid Dynamics: Ten Patient-specific Cases.Journal of clinical images and medical case reports · 2022Article
- A novel Fontan Y-graft for interrupted inferior vena cava and azygos continuation.Interactive cardiovascular and thoracic surgery · 2022Article
- Fontan Revision with Y-Graft in a Patient with Unilateral Pulmonary Arteriovenous Malformation.The Korean journal of thoracic and cardiovascular surgery · 2017Article
- Computational modeling and engineering in pediatric and congenital heart disease.Current opinion in pediatrics · 2015Review
- Hemodynamic study of TCPC using in vivo and in vitro 4D Flow MRI and numerical simulation.Journal of biomechanics · 2015Article
- Relationship of single ventricle filling and preload to total cavopulmonary connection hemodynamics.The Annals of thoracic surgery · 2015Article
- Fontan hemodynamics from 100 patient-specific cardiac magnetic resonance studies: a computational fluid dynamics analysis.The Journal of thoracic and cardiovascular surgery · 2014Article
- Computational modeling of Fontan physiology: at the crossroads of pediatric cardiology and biomedical engineering.The international journal of cardiovascular imaging · 2014Review
- Magnetic resonance imaging-guided surgical design: can we optimise the Fontan operation?Cardiology in the young · 2013Review
- Haemodynamic comparison of a novel flow-divider Optiflo geometry and a traditional total cavopulmonary connection.Interactive cardiovascular and thoracic surgery · 2013Article
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
backgroundUsing a bifurcated Y-graft as the Fontan baffle is hypothesized to streamline and improve flow dynamics through the total cavopulmonary connection (TCPC). This study conducted numerical simulations to evaluate this hypothesis using postoperative data from 5 patients.
methodsPatients were imaged with cardiac magnetic resonance or computed tomography after receiving a bifurcated aorto-iliac Y-graft as their Fontan conduit. Numerical simulations were performed using in vivo flow rates, as well as 2 levels of simulated exercise. Two TCPC models were virtually created for each patient to serve as the basis for hemodynamic comparison. Comparative metrics included connection flow resistance and inferior vena caval flow distribution.
resultsResults demonstrate good hemodynamic outcomes for the Y-graft options. The consistency of inferior vena caval flow distribution was improved over TCPC controls, whereas the connection resistances were generally no different from the TCPC values, except for 1 case in which there was a marked improvement under both resting and exercise conditions. Examination of the connection hemodynamics as they relate to surgical Y-graft implementation identified critical strategies and modifications that are needed to potentially realize the theoretical efficiency of such bifurcated connection designs.
conclusionsFive consecutive patients received a Y-graft connection to complete their Fontan procedure with positive hemodynamic results. Refining the surgical technique for implementation should result in further energetic improvements that may help improve long-term outcomes.
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