ArticleParticle and fibre toxicology2012
A short history of the toxicology of inhaled particles.
Article in Particle and fibre toxicology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
33 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Ambient air pollution exposure, mediating biomarkers and risk of COPD: a cohort study and meta-analysis.European respiratory review : an official journal of the European Respiratory Society · 2025Pooled it
- Exposure to Environmental and Occupational Particulate Air Pollution as a Potential Contributor to Neurodegeneration and Diabetes: A Systematic Review of Epidemiological Research.International journal of environmental research and public health · 2018Pooled it
- Readiness of theFrontiers in toxicology · 2026Article
- 3D printing: Balancing innovation for sustainability with emerging environmental and health risks.iScience · 2025Review
- Biopersistence of man-made vitreous fibres (MMVF) / synthetic vitreous fibres (SVF): advancing from animal models to acellular testing.Particle and fibre toxicology · 2025Review
- Utilizing Martian samples for future planetary exploration-Characterizing hazards and resources.Proceedings of the National Academy of Sciences of the United States of America · 2025Review
- Dust resuspension from the splash of a falling powder: A numerical aerodynamic simulation of a pellet falling onto a powder monolayer.Aerosol science and technology : the journal of the American Association for Aerosol Research · 2025Article
- Effects of different amosite preparations on macrophages, lung damages, and autoimmunity.Journal of molecular medicine (Berlin, Germany) · 2024Article
- Molecular Activation of NLRP3 Inflammasome by Particles and Crystals: A Continuing Challenge of Immunology and Toxicology.Annual review of pharmacology and toxicology · 2024Review
- Computational Fluid Dynamics Simulations of Aerosol Behavior in a High Speed (Heubach) Rotating Drum Dustiness Tester.Particuology · 2023Article
- Editorial: Inorganic particles and fibres: integrating minero-chemistry and hazard assessment for eco-exposome development.Frontiers in chemistry · 2023Article
- Air Pollution: Possible Interaction between the Immune and Nervous System?International journal of environmental research and public health · 2022Review
- Aerogels are not regulated as nanomaterials, but can be assessed by tiered testing and grouping strategies for nanomaterials.Nanoscale advances · 2021Article
- Centrality of Myeloid-Lineage Phagocytes in Particle-Triggered Inflammation and Autoimmunity.Frontiers in toxicology · 2021Review
- Editorial: Immune Mechanisms in the Pathologic Response to Particles, Fibers, and Nanomaterials.Frontiers in immunology · 2021Article
- Adverse outcome pathways as a tool for the design of testing strategies to support the safety assessment of emerging advanced materials at the nanoscale.Particle and fibre toxicology · 2020Review
- Polarization of Immune Cells in the Pathologic Response to Inhaled Particulates.Frontiers in immunology · 2020Review
- Nanoparticle Exposure and Workplace Measurements During Processes Related to 3D Printing of a Metal Object.Frontiers in public health · 2020Article
- Nanoparticles in Construction Materials and Other Applications, and Implications of Nanoparticle Use.Materials (Basel, Switzerland) · 2019Review
- Particle toxicology and health - where are we?Particle and fibre toxicology · 2019Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Particle toxicology arose in order to understand the mechanisms of adverse effects of 3 major particle types that had historically exerted the greatest toll of ill-health--quartz, coal and asbestos. By the middle of the last century rat inhalation studies had been carried out and the pathology documented, but true mechanistic particle toxicology did not really take off until the 1970s when cell culture techniques became available. By the 1980s glass fibres were a major focus of interest and attempts to develop a structure-toxicity paradigm centred on biopersistence. In the 1990s environmental particles dominated the particle toxicology agenda and the cardiovascular system emerged as a target for inhaled particles, raising new challenges for particle toxicologists. We are currently in the era of nanotoxicology where a large and diverse range of new nanoparticles types are under scrutiny.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.