ArticleNorth American journal of medical sciences2010
Post-natal maternal antiretroviral therapy and HIV prevalence among breast-fed infants in Benin, Nigeria.
Article in North American journal of medical sciences, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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1 citing paper in PubMed.
- ESHRE guideline: medically assisted reproduction in patients with a viral infection/disease.Human reproduction open · 2021Article
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4 authors.
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Abstract
backgroundBreastfeeding is an established mode of transmission of human immunodeficiency virus (HIV) infection resulting in clash between socio-cultural values and medical practice.
aimsThis study aims to determine the effect of post-natal maternal antiretroviral therapy on transmission of HIV through breastfeeding. PATIENTS AND
methodsA total of 318 pregnant women were followed from pregnancy to 6 months post- partum. The women were divided into breast-fed and those who did not breast-feed, while the breast-fed were further divided into those on antiretroviral (ARV) and those not on ARV. After 6 months post-partum, dried blood spots were collected from infants born to these women and tested for HIV using polymerase chain reaction.
resultsGenerally, breast-feeding had 4 to 13 fold increase risk of transmission of HIV to infants (OR =7.079 95% CI = 3.768, 13.300; P <0.0001). However, among breast-fed infants, post-natal maternal ARV resulted in reduced prevalence of HIV compared to mothers who did not use ARV during breast-feeding (17.31% VS 92.00%; P<0.0001).
conclusionThe study demonstrates the effectiveness of post-natal maternal ARV. However, research into better feeding options to prevent mother to child transmission of HIV via breast-feeding is advocated.
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