ArticleFrontiers in neurology2012
Clinico-pathological correlations of the most common neurodegenerative dementias.
Article in Frontiers in neurology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it, 51 citations in OpenAlex.
- Exploring the Etiological Links behind Neurodegenerative Diseases: Inflammatory Cytokines and Bioactive Kynurenines.International journal of molecular sciences · 2020Pooled it
- From Gut to Brain: Uncovering Potential Serum Biomarkers Connecting Inflammatory Bowel Diseases to Neurodegenerative Diseases.International journal of molecular sciences · 2024Review
- Fast-track neuropathological screening for neurodegenerative diseases.Free neuropathology · 2024Article
- Design and application of a customizable relational DataBase to assess clinicopathological correlations and concomitant pathology in neurodegenerative diseases.Brain pathology (Zurich, Switzerland) · 2023Article
- Calcium regulation by SERC-A before and during Alzheimer diseaseBiomedica : revista del Instituto Nacional de Salud · 2023Article
- Article
- 4',6-Diamidino-2-Phenylindole Distinctly Labels Tau Deposits.The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society · 2018Article
- Animal Toxins as Therapeutic Tools to Treat Neurodegenerative Diseases.Frontiers in pharmacology · 2018Review
- Alzheimer's disease: Targeting the Cholinergic System.Current neuropharmacology · 2016Review
- Parkinsonism and distinct dementia patterns in a family with the MAPT R406W mutation.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2014Article
- A low-molecular-weight ferroxidase is increased in the CSF of sCJD cases: CSF ferroxidase and transferrin as diagnostic biomarkers for sCJD.Antioxidants & redox signaling · 2013Article
- Microtubule-associated protein tau in bovine retinal photoreceptor rod outer segments: comparison with brain tau.Biochimica et biophysica acta · 2013Article
- Reversible parkinsonism due to a large intracranial tumour.BMJ case reports · 2012Article
- Cognitive impairment and dementia in Parkinson's disease: clinical features, diagnosis, and management.Frontiers in neurology · 2012Article
- Cognitive impairment and dementia-an update.Frontiers in neurology · 2012Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Neurodegenerative dementias are a group of neurological disorders characterized by deterioration in several cognitive domains in which there is selective and progressive loss of specific populations of neurons. The precise neurobiological basis for the different neurodegenerative dementias remains unknown. It is expected that different pathologies reflect different mechanisms, at least early in the neurodegeneration process. The next decades promise treatments directed to causes and mechanisms, bringing an outstanding challenge to clinicians due to heterogeneous clinical presentations with the same molecular pathology. The purpose of this brief review is to describe the key neuropathological features of the most common neurodegenerative dementias (Alzheimer disease, dementia with Lewy bodies and Parkinson's disease dementia, and frontotemporal lobar degeneration) and the relationship with the clinical syndromes described in clinico-pathological studies. We expect this overview contributes for the understanding of this broad topic integrating the two ends of the spectrum: clinical and pathological.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.