ReviewJournal of breath research2012
Microbial volatile compounds in health and disease conditions.
Review in Journal of breath research, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02981550 (Infection Detection by Breath Analysis), which is not on this map. Cited by 46 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Infection Detection by Breath Analysis
Who cites it
46 citing papers in PubMed.
- Sugar Beet Pectin Supplementation Did Not Alter Profiles of Fecal Microbiota and Exhaled Breath in Healthy Young Adults and Healthy Elderly.Nutrients · 2019Trial
- Gas chromatography-mass spectrometry analysis of the secondary metabolites produced by Bacillus paramycoides BOK01 and Microbacterium barkeri BPATH02 and investigation of their antifungal activity against tea pathogens.Antonie van Leeuwenhoek · 2026Article
- Current advances and challenges in microbiome-based mitigation of volatile organic compounds from livestock waste systems.Frontiers in cellular and infection microbiology · 2026Review
- Volatile Organic Compounds Induced upon Viral Infection in Cell Culture: Uniform Background Study with Use of Viruses from Different Families.Molecules (Basel, Switzerland) · 2025Article
- Prevalence of Microorganisms and Suggestion for Potential Contribution of Microorganisms to Volatile Basic Nitrogen Production in Beef at Current Purchase Stages.Food science of animal resources · 2025Article
- Bacterial Volatile Organic Compounds as Potential Caries and Periodontitis Disease Biomarkers.International journal of molecular sciences · 2025Article
- Review
- Analysis of the Urine Volatilome of COVID-19 Patients and the Possible Metabolic Alterations Produced by the Disease.Metabolites · 2024Article
- Evaluation of urinary volatile organic compounds as a novel metabolomic biomarker to assess chronic kidney disease progression.BMC nephrology · 2024Article
- A pattern recognition artificial olfactory system based on human olfactory receptors and organic synaptic devices.Science advances · 2024Article
- The Potential of Fecal Volatile Organic Compound Analysis for the Early Diagnosis of Late-Onset Sepsis in Preterm Infants: A Narrative Review.Sensors (Basel, Switzerland) · 2024Review
- Investigating the action model of the resistance enhancement induced by bacterial volatile organic compounds againstFrontiers in plant science · 2024Article
- Volatile organic compounds in headspace characterize isolated bacterial strains independent of growth medium or antibiotic sensitivity.PloS one · 2024Article
- Potential of volatile organic compounds in the management of insect pests and diseases of food legumes: a comprehensive review.Frontiers in plant science · 2024Review
- Article
- Evaluation of Linkers' Influence on Peptide-Based Piezoelectric Biosensors' Sensitivity to Aldehydes in the Gas Phase.International journal of molecular sciences · 2023Article
- Article
- Oral microbiome as a co-mediator of halitosis and periodontitis: a narrative review.Frontiers in oral health · 2023Review
- The tongue biofilm metatranscriptome identifies metabolic pathways associated with the presence or absence of halitosis.NPJ biofilms and microbiomes · 2022Article
- The Microbiota-Gut-Brain Axis in Psychiatric Disorders.International journal of molecular sciences · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Microbial cultures and/or microbial associated diseases often have a characteristic smell. Volatile organic compounds (VOCs) are produced by all microorganisms as part of their normal metabolism. The types and classes of VOC produced is wide, including fatty acids and their derivatives (e.g. hydrocarbons, aliphatic alcohols and ketones), aromatic compounds, nitrogen containing compounds, and volatile sulfur compounds. A diversity of ecological niches exist in the human body which can support a polymicrobial community, with the exact VOC profile of a given anatomical site being dependent on that produced by both the host component and the microbial species present. The detection of VOCs is of interest to various disciplines, hence numerous analytical approaches have been developed to accurately characterize and measure VOCs in the laboratory, often from patient derived samples. Using these technological advancements it is evident that VOCs are indicative of both health and disease states. Many of these techniques are still largely confined to the research laboratory, but it is envisaged that in future bedside 'VOC profiling' will enable rapid characterization of microbial associated disease, providing vital information to healthcare practitioners.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.