Trial reportJournal of the American Medical Informatics Association : JAMIA
Effects of an online personal health record on medication accuracy and safety: a cluster-randomized trial.
Trial report in Journal of the American Medical Informatics Association : JAMIA. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00251875 (Shared Online Health Records for Patient Safety and Care), which is not on this map. Cited by 47 papers, 8 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Shared Online Health Records for Patient Safety and Care
Who cites it
47 citing papers in PubMed, 8 syntheses or guidelines pooled it, 89 citations in OpenAlex.
- Digital patient safety interventions in primary care: a systematic review and meta-analysis.BMC medicine · 2026Pooled it
- Pooled it
- Adult patient access to electronic health records.The Cochrane database of systematic reviews · 2021Pooled it
- Impact of providing patients access to electronic health records on quality and safety of care: a systematic review and meta-analysis.BMJ quality & safety · 2020Pooled it
- Interventions to increase patient portal use in vulnerable populations: a systematic review.Journal of the American Medical Informatics Association : JAMIA · 2019Pooled it
- The Use and Effects of Electronic Health Tools for Patient Self-Monitoring and Reporting of Outcomes Following Medication Use: Systematic Review.Journal of medical Internet research · 2018Pooled it
- Patients' online access to their electronic health records and linked online services: a systematic review in primary care.The British journal of general practice : the journal of the Royal College of General Practitioners · 2015Pooled it
- Patients' online access to their electronic health records and linked online services: a systematic interpretative review.BMJ open · 2014Pooled it
- Engaging hospital patients in the medication reconciliation process using tablet computers.Journal of the American Medical Informatics Association : JAMIA · 2018Trial
- Evaluation of Multimedia Medication Reconciliation Software: A Randomized Controlled, Single-Blind Trial to Measure Diagnostic Accuracy for Discrepancy Detection.Applied clinical informatics · 2018Trial
- "Why Didn't it Work?" Lessons From a Randomized Controlled Trial of a Web-based Personally Controlled Health Management System for Adults with Asthma.Journal of medical Internet research · 2015Trial
- A web-based personally controlled health management system increases sexually transmitted infection screening rates in young people: a randomized controlled trial.Journal of the American Medical Informatics Association : JAMIA · 2015Trial
- Personal health records: a randomized trial of effects on elder medication safety.Journal of the American Medical Informatics Association : JAMIATrial
- Leveraging technology and human factor principles to improve outpatient medication reconciliation.BMJ open quality · 2025Article
- Incompleteness of Electronic Health Records: An Impending Process Problem Within Healthcare.Healthcare (Basel, Switzerland) · 2025Article
- Reliability and validity of the Chinese version of patient safety culture scale in medication administration.BMC nursing · 2025Article
- The Role of Access Type and Age Group in the Breadth of Use of Patient Portals: Observational Study.Journal of medical Internet research · 2022Observational
- Patients Managing Their Medical Data in Personal Electronic Health Records: Scoping Review.Journal of medical Internet research · 2022Article
- Interprofessional survey on medication reconciliation activities in the US Department of Veterans' Affairs: development and validation of an Implementation Readiness Questionnaire.BMJ open quality · 2022Article
- Health informatics interventions to minimize out-of-pocket medication costs for patients: what providers want.JAMIA open · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors at 4 institutions in 1 country.
Funding
Abstract
objectiveTo determine the effects of a personal health record (PHR)-linked medications module on medication accuracy and safety.
designFrom September 2005 to March 2007, we conducted an on-treatment sub-study within a cluster-randomized trial involving 11 primary care practices that used the same PHR. Intervention practices received access to a medications module prompting patients to review their documented medications and identify discrepancies, generating 'eJournals' that enabled rapid updating of medication lists during subsequent clinical visits. MEASUREMENTS: A sample of 267 patients who submitted medications eJournals was contacted by phone 3 weeks after an eligible visit and compared with a matched sample of 274 patients in control practices that received a different PHR-linked intervention. Two blinded physician adjudicators determined unexplained discrepancies between documented and patient-reported medication regimens. The primary outcome was proportion of medications per patient with unexplained discrepancies.
resultsAmong 121,046 patients in eligible practices, 3979 participated in the main trial and 541 participated in the sub-study. The proportion of medications per patient with unexplained discrepancies was 42% in the intervention arm and 51% in the control arm (adjusted OR 0.71, 95% CI 0.54 to 0.94, p=0.01). The number of unexplained discrepancies per patient with potential for severe harm was 0.03 in the intervention arm and 0.08 in the control arm (adjusted RR 0.31, 95% CI 0.10 to 0.92, p=0.04).
conclusionsWhen used, concordance between documented and patient-reported medication regimens and reduction in potentially harmful medication discrepancies can be improved with a PHR medication review tool linked to the provider's medical record. TRIAL REGISTRATION NUMBER: This study was registered at ClinicalTrials.gov (NCT00251875).
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.