Evidence map›Paper›PMID 22556181›Full record

ReviewJournal of Zhejiang University. Science. B2012

Successful treatment of patients with paraquat intoxication: three case reports and review of the literature.

Qin Zhang, Wei-zhen Wu, Yuan-qiang Lu, Jie-zan Wang, An-dong Shang, Feng Yao, Yan Chen

Abstract readCase ReportsReview
In one paragraph

Review in Journal of Zhejiang University. Science. B, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Severe paraquat poisoning: a 5-year follow-up of a survivor.World journal of emergency medicine · 2026
    Article
  5. Paraquat peril: An insight into a fatal poisoning case.Journal of family medicine and primary care · 2026
    Article
  6. Paraquat Peril: A Retrospective Study from the Frontlines of a Quaternary Care Hospital in South India.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2026
    Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Observational
  14. Paraquat Poisoning: A Case Report.Journal of clinical and diagnostic research : JCDR · 2016
    Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. The preventive effects ofAvicenna journal of phytomedicine
    Article
  20. HIV and paraquat poisoning: fighting fire with fire?Journal of Zhejiang University. Science. B
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Qin ZhangDepartment of Emergency, the First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.
Wei-zhen Wu
Yuan-qiang Lu
Jie-zan Wang
An-dong Shang
Feng Yao
Yan Chen

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo report on three patients with paraquat (PQ) intoxication surviving after combined therapy with hemoperfusion (HP), cyclophosphamide (CTX), and glucocorticoid.

methodsThree patients suffered acute renal failure in a few days after ingesting a lethal amount of PQ. Chest computed tomography (CT) scans revealed obvious pulmonary inflammation, pleural effusion, and fibrous lesions several days after ingestion. HP was performed immediately, followed by large doses of glucocorticoid (methylprednisolone, 500 g/d) and CTX (approximately 4 g).

resultsAfter 50 d of treatments, all three patients were discharged in healthy condition, with chest CT showing small fibrous lesions, exudation, and both lungs clear of auscultation.

conclusionsThe protective effect of the lungs may have been due to timely treatment at adequate doses.

Indexed as

HemoperfusionAdultCombined Modality TherapyCyclophosphamideGlucocorticoidsHerbicidesHumansImmunosuppressive AgentsLung InjuryMaleMultiple Organ FailureParaquatRenal InsufficiencyTreatment OutcomeCyclophosphamideGlucocorticoidsHerbicidesImmunosuppressive AgentsParaquat

Identifiers

PMID22556181
PMCPMC3348234

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.